Coagulation-fibrinolysis is more enhanced in twin than in singleton pregnancies
スポンサーリンク
概要
- 論文の詳細を見る
Aims: To examine whether coagulation-fibrinolysis in late pregnancy in women with twin pregnancies is more pronounced than in women with singleton pregnancies.Patients and methods: The plasma levels of D-dimer, fibrinogen/fibrin degradation products (FDP), and fibrinogen, the platelet count, and the antithrombin activity were assessed from 3 weeks before delivery until postpartum day 7 in 48 women (24 singleton and 24 twin pregnancies) without preeclampsia who underwent cesarean sections.Results: Women with singleton or twin pregnancies gave birth at 37.3±1.2 weeks or 35.2±1.4 weeks, respectively. Compared with singleton mothers, prenatal D-dimer and FDP levels were consistently and significantly higher among women with twin pregnancies. A significantly larger proportion of twin mothers exhibited prenatal levels of D-dimer >5.0 μg/mL, FDP >10.0 μg/mL, fibrinogen <420 mg/mL and antithrombin activity <70%. In addition, prenatal antithrombin activity in plasma was significantly lower.Conclusions: Coagulation-fibrinolysis is more enhanced in women with twin gestation than in women with singleton gestation.
- Walter de Gruyterの論文
著者
-
山田 秀人
北海道大学産婦人科
-
Minakami H
Department Of Obstetrics And Gynecology Hokkaido University Graduate School Of Medicine
-
Yamada Hideto
Department Of Obstetrics And Gynecology Hokkaido University Graduate School Of Medicine
-
Cho Kazutoshi
Department Of Obstetrics And Gynecology Hokkaido University
-
Yamada Takahiro
Department Of Obstetrics And Gynecology Hokkaido University Graduate School Of Medicine
-
Yamada Takahiro
Department Of Obstetrics And Gynecology Hokkaido University
-
Sakuragi Noriaki
Department Of Obstetrics And Gynecology
-
Yamada Takashi
Department Of Obstetrics And Gynecology Hokkaido University Graduate School Of Medicine
-
Minakami Hisanori
Department Of Obstetrics And Gynecology
-
Sakuragi Noriaki
Department Of Gynecology Hokkaido University Graduate School Of Medicine
-
Yamada Hideto
Obstetrics And Gynecology Hokkaido University Graduate School Of Medicine
-
Yamada Takashi
Department Of Animal Science Graduate School Of Agricultural Science Kobe University
-
Morikawa Mamoru
Department Of Obstetrics Hokkaido University Graduate School Of Medicine
関連論文
- ZMVHA-B1, the Gene for Subunit B of Vacuolar H^+-ATPase from the Eelgrass Zostera marina L. Is Able to Replace vma2 in a Yeast Null Mutant(PLANT BIOTECHNOLOGY)
- Monitoring growth and movement of Ralstonia solanacearum cells harboring plasmid pRSS12 derived from bacteriophage φRSS1(PLANT BIOTECHNOLOGY)
- P3-35 妊娠性血小板減少症(GT)/妊娠性アンチトロンビン欠乏症(PIATD)の分娩前後のフィブリノーゲン,FDP,D-dimer,ヘマトクリット値,尿酸値の推移 : 妊娠高血圧症候群(PIH)との関連(Group71 妊娠・分娩・産褥の病理4,一般演題,第60回日本産科婦人科学会学術講演会)
- K3-66 IgG avidityとNested PCRを用いたトキソプラズマ感染スクリーニング法の有用性 : IgM陽性105妊婦の前方視的検討成績(高得点演題19 周産期,高得点演題プログラム,第61回日本産科婦人科学会学術講演会)
- K3-15 破骨細胞においてATP/P2X7受容体シグナルにより誘導される微小管のアセチル化制御を介した骨吸収の分子機構の解析(高得点演題9 女性医学,高得点演題プログラム,第62回日本産科婦人科学会学術講演会)
- P2-88 ヒト胎盤におけるオートファジー関連遺伝子ATG9Bの発現と機能解析(Group54 妊娠高血圧2,一般演題,第62回日本産科婦人科学会学術講演会)
- P3-101 塩酸ラロキシフェン長期投与時の血中遊離型レプチンの変動について(Group78 更年期・老年期3,一般演題,第60回日本産科婦人科学会学術講演会)
- P3-248 産褥HELLP後の習慣流産症例に対するγグロブリン投与の成功例(Group106 不育症2,一般演題,第61回日本産科婦人科学会学術講演会)
- P3-54 胎児水腎症の産科学的特徴ならびに新生児予後に関する後方視的検討(Group73 胎児・新生児の生理3,一般演題,第60回日本産科婦人科学会学術講演会)
- TESE-ICSI後に発生した二絨毛膜性双胎と共存した全胞状奇胎
- P3-272 4-1BB ligandはLPS刺激によりマクロファージに誘導されTNF-α産生維持に関し重要な機能を持っている(Group109 生殖生理2,一般演題,第61回日本産科婦人科学会学術講演会)
- OE-023 Adiponectin Acts as a Positive Indicator of Diastolic Dysfunction in Patients with HCM(OE04,Cardiomyopathy/Hypertrophy (Clinical) (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- P1-162 アンチトロンビン活性(AT)低下や妊娠高血圧症候群(PIH)が産褥期母体体重(BW)減少に及ぼす影響(Group22 妊娠高血圧1,一般演題,第61回日本産科婦人科学会学術講演会)
- 双胎妊娠において Late Preterm Birth (LPB) は異常分娩か?
- 特異的画像所見を示し IgG avidity index と nested PCR にて診断したトキソプラズマ脳症の1例
- 羊水流出に関する診断法 (特集 羊水・羊膜)
- P3-237 切PCR法を用いた切迫早産症例の羊水中マイコプラズマ属の検出(Group105 周産期感染症3,一般演題,第61回日本産科婦人科学会学術講演会)
- 症例から見た妊娠高血圧症候群の病態とその管理
- 妊娠高血圧症候群と遺伝因子 (特集 産科医療における遺伝学) -- (産科異常と遺伝因子)
- 3) 先天性サイトメガロウイルス感染症に対する免疫グロブリン療法(胎児治療の最近の進歩,クリニカルカンファレンス6,生涯研修プログラム,第60回日本産科婦人科学会生涯研修プログラム・卒後研修プログラム,研修コーナー)
- 9) TORCH症候群(18.産科感染症の管理と治療,D.産科疾患の診断・治療・管理,研修コーナー)
- P4-15 原因不明習慣流産に対する免疫グロブリン大量療法は,末梢血免疫細胞における分子発現を変化させるか(Group95 不育症1,一般演題,第60回日本産科婦人科学会学術講演会)
- 3) 先天性サイトメガロウイルス感染症に対する免疫グロブリン療法(クリニカルカンファレンス6 胎児治療の最近の進歩,生涯研修プログラム,第60回日本産科婦人科学会学術講演会)
- 血液型不適合妊娠 (周産期臨床検査のポイント) -- (産科編 各種病態で必要な検査)
- 先天性サイトメガロウイルス感染症と免疫グロブリン療法 (特集 妊産婦の感染症とその対策)
- 胎児医療の現状と将来--母子感染治療と予防における新たな試み (周産期診療プラクティス)
- 血液凝固異常合併妊婦の管理 (特集 ハイリスク合併妊婦の増加を考える--キャリーオーバー疾患管理のポイント)
- 妊娠中毒症と抗リン脂質抗体 (特集 抗リン脂質抗体症候群)
- Vaginal and Cervical pH in Bacterial Vaginosis and Cervicitis during Pregnancy
- 遺伝性球状赤血球症合併妊娠の産科管理
- Suppression of Tumorigenicity and Induction of Senescence on Human Endometrial Carcinoma Cell Lines by Transfer of Normal Human Chromosomes
- 原因不明の習慣流産婦人における自然流産組織の染色体異常
- FRS-151 Efficacy of Nifekalant hydrochloride administration in patients with life-threatening ventricular arrhythmia due to ischemic cardiac disease(Sudden Cardiac Death (A) : FRS18)(Featured Research Session (English))
- FRS-047 Coronary Reperfusion Improved In-hospital Outcome of High Risk Patients in Acute Myocardial Infarction(New Therapeutic Strategies in Myocardial Infarction (IHD) : FRS6)(Featured Research Session (English))
- 6 More Than 10 Years Clinical Follow-up after Balloon Angioplasty(Symposium 7 (SY7) (IHD) : Longterm Prognosis of Japanese Patients with Coronary Disease : Medical Therapy, PCI, Surgical Intervention)(Special Program)
- 6 Electrical storm (ES) patient with acute coronary syndrome (ACS) can be improved in-hospital and long term prognosis with undergo complete revascularization (CS)(Symposium 6 (SY6) (IHD) : Treatment for CPA : Improving the Current Status?)(Special Progra
- 4 Long-term prognosis of elderly coronary artery disease after successful percutaneous coronary intervention(Plenary Session 9 (PL9) (H) : Cardiovascular Treatment in the Elderly : In Whom? How Aggressive?)(Special Program)
- How Do Customers Move in a Supermarket? : Analysis by Real Observation and Agent Simulation
- PJ-334 Measurement of the Plasma Adiponectin Level is Useful for the Prediction of Metabolic Syndrome : Result from KING Study(PJ056,Preventive Medicine/Epidemiology/Education 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japan
- PJ-197 Common Variants in and around the Adiponectin Gene Associated with Plasma Adiponectin Level : Result from KING Study(PJ033,Preventive Medicine/Epidemiology/Education 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese
- Correlation Between Mercury Concentrations in Hair and Dental Amalgam Fillings
- Could Myocardial Staining with Computed Tomography Just after Direct PTCA for Acute Myocardial Infarction Predict the Size of Infarction? (X-ray/CT/MRI/DSA 8 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-039 Postprandial Left Ventricular Performance Change in Patients with Acute Myocardial Infarction(Nuclear Cardiology 3 (I) : PJ7)(Poster Session (Japanese))
- 双胎妊娠において Late Preterm Birth (LPB) は異常分娩か?
- Response of osteoblasts and osteoclasts in regenerating scales to gravity loading
- A catalog of 106 single-nucleotide polymorphisms (SNPs) and 11 other types of variations in genes for transforming growth factor-β1 (TGF-β1) and its signaling pathway
- IS-125 KL-6 and SP-A Levels in Amniotic Fluid as Markers of Fetal Lung Maturation
- A case of congenital toxoplasmosis whose mother demonstrated serum low IgG avidity and positive tests for multiplex-nested PCR in the amniotic fluid
- 4G/5G Variant of Plasminogen Activator Inhibitor-1 Gene and Severe Pregnancy-Induced Hypertension : Subgroup Analyses of Variants of Angiotensinogen and Endothelial Nitric Oxide Synthase
- A1166C variant of angiotensin II type 1 receptor gene is associated with severe hypertension in pregnancy independently of T235 variant of angiotensinogen gene
- Complete hydatidiform mole with coexisting dichorionic diamniotic twins following testicular sperm extraction and intracytoplasmic sperm injection
- Coagulation-fibrinolysis is more enhanced in twin than in singleton pregnancies
- P1-IS-66 The association between Lactobacillus species and bacterial vaginosis-related bacteria, and bacterial vaginosis scoring in Japanese pregnant women
- P-IS-90 Critical periods for the effects of maternal deprivation on circadian clock, stress-responsiveness of adrenal cortex and growth in rats(Perinatology 5,Group 110,International Session)
- P-IS-73 Detection of vaginal lactobacillus and mycoplasma in early pregnancy and its relationship with preterm birth(Perinatology 1,Group 106,International Session)
- Common Conceptions and Acceptance of Homeless People : A Questionnaire Study of the Citizens of Sapporo, Japan
- Prenatal diagnosis and fetal therapy of congenital cystic adenomatoid malformation type I of the lung: a report of five cases
- IS-66 An infertile woman with steroid cell tumor presenting hyperandrogenism : a case report
- Familial 15p tetrasomy due to supernumerary marker 15 chromosome associated with Robertsonian translocation between chromosomes 13 and 14
- Morphological Aspects of Ectopia Cordis : Four Case Reports and a Review of the Literature
- Cytogenetic study on uterine leiomyoma(Abstracts of the 49th Annual Meeting of the Society of Chromosome Research)
- Molecular genetic study on sex determination, differentiation and sexual differentiation anomaly(Abstracts of the 49th Annual Meeting of the Society of Chromosome Research)
- Molecular and cytogenetic prenatal identification of supernumerary marker chromosomes (SMCs)(Abstracts of the 49th Annual Meeting of the Society of Chromosome Research)
- IS-124 Persistent Detection of Alfa-fetoprotein in the Vagina without Overt Preterm Premature Rupture of the Membranes : Clinical and Chemical Characterizations
- IS-92 Analyses of Factors Contributing Vulnerability to Antenatal Periventricular Leukomalacia Induced by Hemorrhagic Hypotension in Chronically Instrumented Fetal Sheep
- Silent Premature Rupture of Membranes, Detected and Monitored Serially by an AFP Kit
- Comparison of an Improved AFP Kit with the Intra-Amniotic PSP Dye-Injection Method in Equivocal Cases of Preterm Premature Rupture of the Fetal Membranes
- Subchromosomal Mapping of a Putative Transformation Suppressor Gene on Human Chromosome 1
- Cytoreductive surgery combined with organ resection for advanced ovarian carcinoma
- Thromboprophylaxis with low molecular weight heparin in thrombophilia-complicated pregnancy
- Management of Pregnancy with Congenital Antithrombin III Deficiency : Two Case Reports and a Review of the Literature
- IS-102 Lens Culinaris Agglutinin Reactive AFP in Prenatal Screening of Down Syndrome
- IS-25 Dominant Negative Mutation of p53 Tumor Suppressor Gene the in Pathogenesis of Endometrial Carcinoma
- IS-24 Combined Conventional and Immunocytochemical Cytology for Peritoneal Washings in Endometrial Carcinoma
- IS-9 Preoperative Serum SCC, CEA, CA125, and CA19-9 Levels and Surgicopathological Extension of Cervical Carcinoma
- Assessment of congenital nasal stenosis by shaded surface display reconstruction images
- Prenatal trisomy 21 screening using the Lens culinaris agglutinin-reactive alpha-fetoprotein ratio
- Specific ultrasound findings associated with fetal chromosome abnormalities
- High Prevalence of Multiple Human Papillomavirus Infection in Japanese Patients with Invasive Uterine Cervical Cancer
- Intravenous immunoglobulin therapy for aspirin-heparinoid-resistant antiphospholipid syndrome
- Pregnancy-induced antithrombin deficiency
- Treatment of cervical cancer with adjuvant chemotherapy versus adjuvant radiotherapy after radical hysterectomy and systematic lymphadenectomy
- Paraaortic Lymph Node Metastasis in Gynecologic Malignancies
- Survival and prognosticators of node-positive cervical cancer patients treated with radical hysterectomy and systematic lymphadenectomy
- Epigenetic abnormality of SRY gene in the adult XY female with pericentric inversion of the Y chromosome
- Global gene profiling and comprehensive bioinformatics analysis of a 46,XY female with pericentric inversion of the Y chromosome
- A surviving case of papillorenal syndrome with the phenotype of Potter sequence
- Risk factors for lower-limb lymphedema after surgery for cervical cancer
- Clusterin is a potential molecular predictor for ovarian cancer patient's survival: targeting Clusterin improves response to paclitaxel
- Circulating cytokines during early pregnancy in women with recurrent spontaneous abortion : Decreased TNF-α levels in abortion with normal chromosome karyotype
- Bioactivity of human chorionic gonadotropin produced in frozen-thawed embryo transfer cycles with exogenous hormone replacement
- Diffusion-weighted Imaging of a Malignant Brenner Tumor
- Clinical features of abruptio placentae as a prominent cause of cerebral palsy
- A type of familial cleft of the soft palate maps to 2p24.2–p24.1 or 2p21–p12
- Antithrombin activity, platelet count, hemoglobin concentration and hematocrit value determined immediately before vaginal delivery among healthy women
- ISO-3-4 Renin is elevated in monochorionic diamniotic twins who have birthweight discordance but not twin-to-twin transfusion syndrome(Group 3 Perinatology,IS Award Candidate,International Session)
- ISP-6-2 Recombinant H2 relaxin inhibits apoptosis with induction of cell proliferation in human uterine leiomyoma(Group 6 Oncology 6,IS Poster,International Session)
- ISP-7-1 Relaxin has anti-apoptotic effects on human trophoblast-derived HTR-8/SV neo cells(Group 7 Reproduction,IS Poster,International Session)
- Less Invasive New Vaginoplasty Using Laparoscopy, Atelocollagen Sponge, and Hand-Made Mould
- Prophylactic Intravenous Immunoglobulin Injections to Mothers with Primary Cytomegalovirus Infection