生薬によるアジュバント関節炎の抑制(第1報)

概要

論文の詳細を見る
Anti-adjuvant arthritis effect of nine herbs, which are frequently used for the treatment of rheumatoid arthritis in oriental medicine, was studied in rat. Adjuvant arthritis was found to be suppressed markedly by oral administration of Paeoniae Radix, Atractylodis Rhizoma and Angelicae Radix, moderately by Ledebouriellae Radix Ephedrae Herba, and Moutan Cortex, but not by Cinnamomi Cortex and Sinomeni Caulis et Rhizoma. Administration of Atractylodis Lanceae Rhizoma apparently accelerated the development of adjuvant arthritis. Of those herbs which were active in the present experiment, only Angelicae Radix is known in literature to have some anti-inflammatory effect on acute inflammation: Paeoniae Radix and Ledebouriellae Radix are not known to have such effect. They may have anti-inflammatory effect only on inflammation involved in the process of development of ad juvant arthritis, which is systemic and differs from that involved in the process of usual acute inflammation.
日本生薬学会の論文
1982-03-20