Time-lapse analysis of laser phase shift for noninvasive discrimination of human normal cells and malignant tumor cells(CELL AND TISSUE ENGINEERING)
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概要
- 論文の詳細を見る
Time-lapse analysis of phase shift using phase-shifting laser microscopy (PLM) revealed that the laser phase shifts of primary normal human prostate epithelial cells (PRECs) and human prostatic carcinoma epithelial cell line (PC-3) cells during the mitotic phase were markedly higher than those in the interphase. The phase shift of PC-3 cells during the interphase was markedly lower than that of PRECs throughout the cell cycle. In conclusion, it was proposed that adherent PC-3 cancer cells could be noninvasively discriminated from normal adherent PRECs by the periodical measurement of phase shift using PLM during culture.
- 2012-11-00
著者
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Takagi Mutsumi
Division Of Biotechnology And Macromolecular Chemistry Graduate School Of Engineering Hokkaido Unive
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Shibaki Yuhei
Division Of Applied Science And Engineering Muroran Institute Of Technology
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Shibaki Yuhei
Division of Biotechnology and Macromolecular Chemistry, Graduate School of Engineering, Hokkaido University
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