M-sequences from neural loop circuits

概要

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In circuit theory it is well known that loop circuit with a feedback link generates a pseudo-random sequence including an M-sequence with maximum period length. On the other hand, it remains unclear how memory is stored in neural circuits of the human brain. We propose that M-sequence composes temporal independent basis functions in brain neural network for communication and memory storage. We have already shown its feasibility by computer simulations that show a loop circuit can be copied to another area by back-propagation leaning algorithm; this is a key function of brain intelligence, which includes functions such as memory, association, reasoning, and abstraction. We found M-sequence responses in the instantaneous firing rates from cultured neural networks of published data and our own data, which suggest the existence of loop circuits with a feedback link composed of 3 to 5 neuron cells. Analyzing the time sequence of spike intervals of cultured neural network with the "auto mutual-information function," we also find evidence that suggests the existence of loop circuits with a feedback link composed of 3, 4 neurons.
2012-01-12