P-12 炭酸含有アパタイトと低出力超音波パルス応用による骨形成促進効果(生体反応,一般講演(ポスター発表),第59回日本歯科理工学会学術講演会)

概要

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Particulates of β-TCP, carbonate apatite heated at 500℃ (500CA) and CA sintered at 700℃ (700CA) were implanted into Ti-mesh tubes in bone defects in low jaws of adult dogs for 2 and 4 weeks and low-intensity pulsed ultra sound (LIPUS) at 3 MHz was exposed for 15 minutes everyday. The efficacy of LIPUS together with the materials on the new bone formation and also on the resorption of the materials was assessed histologically and by morphometric analysis using Villanueva bone staining. At 2 weeks, LIPUS significantly increased new bone formation with 500CA, although it did not affect the resorption of the materials except 700CA, which was resorbed more with LIPUS exposure. At 4 weeks, however, no significant influences were observed with LIPUS and 500CA was as effective as β-TCP in terms of new bone formation.
2012-03-25