白血球表面の剪断応力に血漿層が及ぼす影響 : 二層流モデルによる解析(生体(2),一般講演)

概要

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The shear stress distribution on the surface of a leukocyte adhered to the microvessel wall was analyzed by a numerical simulation, taking the presence of a cell-free layer into account. The blood flow was modeled as a two-phase flow, consisting of a plasma flow in a cell-free layer adjacent to the vessel wall and the cell-rich flow in the central region of the vessel. It is assumed that the fluid in both regions is Newtonian with different viscosities and that the cell free layer covers the surface of the adherent leukocyte with a certain thickness. The flow field was calculated by a finite element method applied to the Stokes equation and the continuity equation. It was found that the profile of the shear stress distribution is not qualitatively affected by the presence of the cell-free layer but the maximum magnitude of the shear stress on a leukocyte may be reduced down to a low value that would not be realized in the absence of the plasma layer.
日本流体力学会の論文
2008-09-04