AM06-28-002 毛細血管壁の透過性の解析(生物流体・生体流体(1),一般講演)

概要

論文の詳細を見る
The vascular endothelial cells are the principal barrier to, and regulator of, material exchange between circulating blood and body tissues. We consider the paracellular transport of fluid across the endothelial cells, and estimate the hydraulic conductivity to water, Lp, of the microvessel wall, by a fluid-mechanical analysis for a flow through serial pathways of the endothelial surface glycocalyx, the interendothelial cleft with junction strands and their discontinuous leakages, up to the interstitial space. The 3D structure of the pathway is found to affect largely the velocity profile of the fluid. The flow is concentrated near the streamlines going straight into the gap of the junction strand, so that the fluid stresses on the endothelial surface are locally increased in the region along these streamlines.
日本流体力学会の論文
2006-09-05