脳血管障害に関するマルチスケール・マルチフィジックス解析(特別講演3)

概要

論文の詳細を見る
Cerebrovascular disorders such as cerebral aneurysms or atherosclerosis are reported to be caused by the degeneration of arterial walls such that mechanical stresses induced by blood flow affects mass transport of the endothelial cells and then leads to hardening of arterial walls. In order to obtain a better understanding of the degeneration of arterial walls, the authors have been developing a multi-scale and physics numerical simulation system "M-SPhyR (M__-ulti-S__-cale and <Phy>__-sics SimulatoR__-) Circulation". The paper presents the main features of M-SphyR, which consists of three programs and the modules to connect three programs. The analyses are carried out for three different cases: 1) multi-scale analysis for the cerebral arterial circle of Wills, 2) analysis of blood flow-arterial wall interaction for a cerebral aneurysm, and 3) multi-physics analysis of atherosclerosis in the carotid artery. The results are compared to those by the conventional methods and are discussed for the further improvement of the simulation system.
日本流体力学会の論文
2007-08-06