循環系血流解析における末梢血管網を考慮した流出境界条件のモデリング(流体工学,流体機械)

概要

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In order to achieve an in vivo simulation of the circulatory system, it is important to apply appropriate physiological conditions such as physical properties, models, and boundary conditions. In this paper, we focus on modeling of outflow boundary conditions taking account of the effects of peripheral vessel network for hemodynamic simulation. The network of cerebral arteries is modeled including the arteries and arterioles, whose sizes can not be resolved by MRA. The peripheral resistance, compliance, and impedance are treated by one-dimensional simulation and zero-dimensional model of the network. The present method is applied to two patient-specific models with or without occlusion in the cerebral arterial circle of Willis. As a result, particularly in the case with occlusion, the present method shows a significant difference in the flow rate of each artery and also improvement in blood flow distribution in the network comparing to the simulation with free-stream boundary condition.
社団法人日本機械学会の論文
2008-04-25