(4)分娩時胎児心拍数陣痛図パターンと周産期脳障害に関する臨床的および基礎的研究(シンポジウム3「新生児脳障害の減少に向けて」,<特集>第62回日本産科婦人科学会・学術講演会)

概要

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Fetal heart rate monitoring is widely spread as a tool of the management of the intrapartum monitoring. On 2010 Japan Obstetrical and Gynecological meeting classified fetal heart rate monitoring pattern in 5 classes. We investigated the relationship between this 5 classification and the fetal acidosis in one delivery center. And we clearly showed the 5 classes had strong relationship with fetal pH, pO2, and BE. In the analysis of 3,600 deliveries in the same delivery center, we showed the obstetrical responses to each class (real-time triage method) improved not only fetal acidosis but also intrapartum FHR monitoring pattern. And we gave same asphyxia (pH6.9 BE-12, 50min) using partial cord occuluder to full term fetal lamb, and found that there are differences in the grade of histological cerebral insufficiency even after the same asphyxia, same bradycardia insult. And finally we concluded that fetal blood pressure has relation to the occurrence of the severity of cerebral damage. And the observation of the baby is necessary for the diagnosis of the perinatal cerebral palsy.
2010-12-01