Introduction of the General Rules for Clinical and Pathological Studies on Cancer of the Colon, Rectum and Anus:Evaluation of invasion distance and budding appearance in early colorectal cancer
スポンサーリンク
概要
- 論文の詳細を見る
Indication of endoscopic treatment for colorectal cancer with submucosal invasion( called as early colorectalcancer) is expanding although such lesions have a high potential to metastasize. Therefore, pathologicalevaluation of early colorectal caner is important. In practice, surgical resection is required after endoscopictreatment of early colorectal cancer when lymphovascular invasion is obvious, the treated lesion is a poorlydifferentiated adenocarcinoma or an undifferentiated carcinoma, or carcinoma is invading massively to thevicinity of the stump. However, lymph node metastasis is indeed found only at about 10 %, nevertheless anadditional colectomy is performed to exclude the risk of lymph node metastasis. From the viewpoint of pathology,the measurement of vertical invasion distance and/or the evaluation of tumor budding appearancein its invasive front may be useful for the precise prediction of lymph node metastasis in patients with earlycolorectal cancers. Then, the Project Committee for Handling Submucosal Carcinomas, the Japanese Societyfor Cancer of the Colon and Rectum, have recently collected 865 cases of early colorectal cancers and analyzedclinicopathological factors including the distance of submucosal invasion. Subsequently, the committesuggested the outline to determine the early colorectal cancer without lymph node metastasis and moreoverclarified that budding appearance is important to predict lymph node metastasis in patients with early colorectalcancers. In the present article, we explain the detailed discussion in the process of establishment forthe outline.
- 獨協医科大学の論文
- 2009-03-25
著者
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Kazuhito Ichikawa
Department of Surgical and Molecular Pathology
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Ichikawa Kazuhito
Department Of Surgery Kyowa Central Hospital
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Hidetsugu Yamagishi
Department Of Gastroenterology Dokkyo Medical University School Of Medicine
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Hidetsugu Yamagishi
Department Of Surgical And Molecular Pathology・department Of Gastroenterology Dokkyo Medical Univers
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Tokiko Kimura
Department Of Surgical And Molecular Pathology Dokkyo Medical University School Of Medicine
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Kimura Tokiko
Department of Surgical and Molecular Pathology
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Yamagishi Hidetsugu
Department of Gastroenterology, Dokkyo Medical University School of Medicine
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Yamagishi Hidetsugu
Department of Surgical and Molecular Pathology : Department of Gastroenterology, Dokkyo Medical University School of Medicine
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