小児もやもや病患者の知能と頭部MRI所見の検討(<特集>小児科学教室大澤真木子教授開講5周年記念)

概要

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In a group of 23 cases between the ages of 6 and 26 years with moyamoya disease, the brain MRI findings were correlated with intelligence as measured by the Wechsler intelligence tests (19, WISC-R and 4, WAIS-R). Normal neurological findings were observed in all the 11 cases (100%) who had normal brain MRI findings, and in 7 (58%) of 12 with abnormal brain MRI findings; this difference was statistically significant. Normal IQ was found in 9 (82%) of the 11 cases who had normal brain MRI findings, and in 3 (25%) of 12 with abnormal brain MRI findings; this difference was also statistically significant. There were no significant differences in the FIQ, PIQ and VIQ between the cases with normal brain MRI findings and those with a single cerebral infarct on MRI. Cases with multiple cerebral infarcts with or without cerebral atrophy on MRI had significantly lower FIQ, VIQ and PIQ than those with normal brain MRI findings. These results suggest that multiple cerebral infarcts are related to mental impairment in cases with moyamoya disease.
2000-06-25