急性大動脈解離,手術後の腰下肢しびれに対しパロキセチンが奏効した1例

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In this article we report the effects of paroxetine on numbness in the back and lower extremities after surgery for acute aortic dissection. The ascending aorta of a 59 year-old male patient was replaced after acute dissection (Stanford A). His postoperative condition was good. However, he developed severe numbness and pain in his back and lower extremities due to intraoperative, multiple spinal cord infarctions. The numbness and pain led to anorexia, and sleep and psychological disturbances. No relief was achieved with oral analgesics, suppositories or epidural anesthesia. We then started paroxetine, a selective serotonin reuptake inhibitor. His symptoms improved after 3 days of medication, and disappeared completely on the 10th day.
東京女子医科大学の論文