TRAUMATIC RUPTURE OF THE SPLEEN IN THE NEWBORN INFANT WITH HEMOPHILIA A

概要

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Traumatic rupture of the normal spleen in the neonatal period is a quite rare condition. Only about 40 newborn cases of this disease have been reported in the literature. A case reported here is an additional one accompanied with true hemophilia A. Splenectomy was forced because complete stop of the bleeding was impossible during the operation, although there has been increaseing pressure on surgenons to avoid the splenectomy on account of its role in immune response. No prophylactic antibiotics were used postoperatively. Periodical assay of immunoglobulin showed no deficiency of IgM which is usually decreased after splenectomy. Quantitative estimation of acute phase reactants (APR) is very useful to detect the early infection in post-splenectomy. Careful follow-up should be done by measurement of APR as well as IgM at a regular interval and if any minimal infectious signs appear, then appropriate antibiotics should be administered.
名古屋市立大学の論文
1981-06-04