5 Alpha-Reductase and Aromatase Inhibitory Constituents from Brassica rapa L. Pollen
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概要
- 論文の詳細を見る
In the screening of biologically active constituents from Brassica rapa pollen, the supercritical CO_2 fluid extract (SFE-C0_2) showed potent 5α-reductase and aromatase inhibiting activity. The SFE-CO_2 extract was separated by various chromatographic methods to give two new phytosterol derivatives, 24-methylenecholesterol linolenate (1) and cycloeucalenol linolenate (2), as well as eight known compounds, 24-methylenecholesterol palmitate (3), cycloeucalenol (4), pollinastanol (5), 24-methylenecholesterol (6), linolenic acid (7), palmitic acid (8), monolinolein (9) and monopalmitin (10), compounds 7 and 9 showed potent 5α-reductase inhibitory activity; compounds 1-6 and 10 showed potent aromatase inhibitory activity.
- 公益社団法人日本薬学会の論文
- 2009-04-01
著者
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Li Kun
Department Of Biological Engineering College Of Environment & Chemical Engineering Yanshan Unive
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Li Kun
Department Of Traditional Chinese Medicine Shanghai Institute Of Pharmaceutical Industry
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Li Kun
Department Of Applied Physics And Materials Research Center The Hong Kong Polytechnic University
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Yang Nian-yun
Department Of Traditional Chinese Medicine Shanghai Institute Of Pharmaceutical Industry
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Yang Yi-fang
Department Of Traditional Chinese Medicine Shanghai Institute Of Pharmaceutical Industry
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LI Yong-Hui
Department of Traditional Chinese Medicine, Shanghai Institute of Pharmaceutical Industry
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JIN Li-Li
Department of Traditional Chinese Medicine, Shanghai Institute of Pharmaceutical Industry
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KONG De-Yun
Department of Traditional Chinese Medicine, Shanghai Institute of Pharmaceutical Industry
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Li Yong-hui
Department Of Traditional Chinese Medicine Shanghai Institute Of Pharmaceutical Industry
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Jin Li-li
Department Of Traditional Chinese Medicine Shanghai Institute Of Pharmaceutical Industry
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Kong De-yun
Department Of Traditional Chinese Medicine Shanghai Institute Of Pharmaceutical Industry
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