Morphological Effects of Sinefungin, an Inhibitor of S-Adenosylmethionine-Dependent Methyltransferases, on Anabaena sp. PCC 7120
スポンサーリンク
概要
- 論文の詳細を見る
Anabaena cells develop regular one-dimensional filaments through cell division in planes parallel to each other. A gcvP mutant displayed morphological defects such as filaments with sharp bends and/or branching and irregular cell clumps. The defects probably result from depletion of S-adenosylmethionine (AdoMet), because they were rescued by the application of methionine, an AdoMet precursor, and because sinefungin, a strong inhibitor of AdoMet-dependent methyltransferases, caused morphological abnormalities in wild-type Anabaena similar to those of the mutant. AdoMet-dependent methylation is involved in the spatial regulation of cell polarity in Anabaena.
- 日本微生物生態学会の論文
著者
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Machida Yasunori
Division Of Biological Science Graduate School Of Science Nagoya University
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Syono Kunihiko
Inplanta Innovations Inc.
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Syono Kunihiko
Inplanta Inovations Inc.
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Kawaguchi Masayoshi
Department Of Biological Sciences Graduate School Of Science The University Of Tokyo
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FUJITA HIRONORI
Division of Theoretical Biology, National Institute for Basic Biology
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Fujita Hironori
Division Of Theoretical Biology National Institute For Basic Biology
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