黄色ブドウ球菌におけるメチシリン耐性遺伝子mecAの水平伝播の可能性

概要

論文の詳細を見る
The main way that methicillin-resistant Staphylococcus aureus (MRSA) is spread is through contact in hospitals but there is also the possibility of horizontal transmission of the methicillin resistance gene mecA among S. aureus since mecA is located on the mobile element SCCmec. In this study, through the typing of MRSA and methicillin-susceptible S. aureus (MSSA) by pulse field gel electrophoresis (PFGE), MSSA and MRSA belonging to a similar genetic group were identified. When mecA was deleted from the MRSA, its PFGE pattern became similar to that of MSSA. Our results therefore suggest that there is a strong possibility that MRSA spreads by the horizontal transmission of mecA to MSSA as well as through contact.
日本医療薬学会の論文
2008-10-10