エチレングリコール水溶液における液体ガラス転移の複素熱容量測定(平成18年度第52回低温生物工学会年会)

概要

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Vitrification provides a general solution to the problem of organ preservation, because it allows to avoid both the direct and indirect damaging effects of freezing. Generally, water in the cell crystallizes below a melting point, and ice crystals cause destruction in the cell. This is a serious problem on freeze preservation. Cryoprotectant is a material that enables cells to cryopreserve. Ethylene glycol ((HO)CH_2CH_2(OH), EG) aqueous solution is well known as cryoprotectant. Fahy et al. reported the benefit of substituting the weaker glass-former EG to the strong glass-former 1,2-propanediol on toxicity in their solution. Therefore, investigating the nature of a glass transition of EG aqueous solution is very important. Using Modulated Temperature Differential Scanning Calorimetry, MDSC, we investigated thermal relaxation around a glass transition temperature (T_g) on EG solution (20, 30, 40, 50, 60, 70, 80 mol%). The underlying heating rate was 0.5 ℃/min, modulation amplitude ± 0.5 ℃, modulated period 100, 60, 40 s.
低温生物工学会の論文
2006-12-30