52(PO7) ヒバ油副生水からのヒノキチオール抽出方法(ポスター発表の部)

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Extracts of trees have been used as drugs, insecticides, perfumes, and dyes since a long time ago. But those were recently used a little for development of chemicals having potent effects. More recently, from a safe point of view in those chemicals, extracted compornents of trees were focused again because of variety and mild effect on organism. Hinokitiol is a compornent which have been studied best in practice. Purified oil of Thujopsis dolabrara var. hondae Makino (Aomori hiba) and Chamaecyparis taiwanesis Masamune et Suzuki (Taiwan hiba) contain about 1 wt% of Hinokitiol, which inhibits the growth of a wide variety of bacterial species even in a few thousand-fold dilution condition. Extraction of hiba oil gives a large amount of aqueous layer as a by-product, That aqueous layer contains a very small amount of Hinokitiol, but has never been tried to collect and purify. Now we established industrial technology in production of Hinokitiol with low cost and high purity, from that aqueous layer. Crude oil was recovered with an absorptive resin from aqueous layer which was obtained by steam distillation of Ma chips, and purified to give pure Hinokitiol effectively.
天然有機化合物討論会の論文
1998-08-31

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