38 カルタミンの合成研究

概要

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In 1979, we proposed the revised structure 1 for carthamin, the red pigment of the flowers of Safflower (Carthamus tinctorius L.). In connection with the synthetic studies of 1, the synthesis of dehydro-3,3'-diacetyl-5,5'-methylenedifilicinic acid (2), dehydro-3,3'-bis(p-hydroxycinnamoyl)-5,5'-methylenedifilicinic acid (3), and dehydro-2,2'-bis(p-hydroxycinnamoyl)-4,4'-dihydroxy-4,4'-dimethyl-1,1',3,3',5,5'-hexaoxo-6,6'-methylenedicyclohexane (5), the analogs of 1, have been carried out. Interestingly, cotton or silk could be dyed with 4 and 5 in a similar manner as carthamin. Further, 2,6-diacetyl-4-C-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-4-hydroxycyclohexane-1,3,5-trione (25), a building block for the synthesis of 1, was obtained by the C-glucosylation of 2,6-diacetyl-1,3,4,5-benzenetetrol (24) with α-acetobromoglucose.
天然有機化合物討論会の論文
1985-09-07