Augmentation of Polysialic Acid by Valproic Acid in Early Postnatal Mouse Hippocampus and Primary Cultured Hippocampal Neurons(MEDICAL BIOTECHNOLOGY)
スポンサーリンク
概要
- 論文の詳細を見る
We examined the effects of valproic acid(VPA) on hippocampal neurons. Prenatal VPA exposure significantly increased polysialic acid(PSA) expression in the early postnatal mouse hippocampus. Moreover, VPA treatment significantly enhanced PSA expression in primary cultured hippocampal neurons and stimulated neurite growth. Our results suggest that VPA exposure in ovo affects hippocampal development.
- 社団法人日本生物工学会の論文
- 2008-02-25
著者
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Gao Yong
Department Of Epigenetic Medicine Interdisciplinary Graduate School Of Medicine And Engineering Univ
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NAGAI Kaoru
Department of Epigenetic Medicine, Interdisciplinary Graduate School of Medicine and Engineering, Un
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Hirasawa Takae
Department Of Epigenetic Medicine Interdisciplinary Graduate School Of Medicine And Engineering Univ
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Nagai Kaoru
Department Of Epigenetic Medicine Interdisciplinary Graduate School Of Medicine And Engineering Univ
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Nagai Kaoru
Department Of Applied Biological Chemistry College Of Agriculture Osaka Prefecture University
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Kodaira Fumiaki
Department Of Epigenetic Medicine Interdisciplinary Graduate School Of Medicine And Engineering Univ
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Natori Takamitsu
Department of Epigenetic Medicine, Interdisciplinary Graduate School of Medicine and Engineering, Un
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Natori Takamitsu
Department Of Epigenetic Medicine Interdisciplinary Graduate School Of Medicine And Engineering Univ
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Nagai Kaoru
Department Of Epigenetic Medicine Interdisciplinary Graduate School Of Medicine And Engineering Univ
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