INHIBITORY EFFECTS OF XANTHONE ON PARAQUAT- AND NaNO_2-INDUCED GENOTOXICITY IN CULTURED CELLS
スポンサーリンク
概要
- 論文の詳細を見る
The inhibitory effects of xanthone on genotoxicity induced by paraquat and NaNO_2 in cultured Chinese hamster lung (CHL) cells were examined. Xanthone forms the central core of xanthones. Xanthones are present in mangosteen, which is widely used as health food because of its many pharmacological properties. Paraquat (PQ, a superoxide anion generator) and NaNO_2 induce genotoxic effects, including sister chromatid exchange (SCE) and decreased cell cycle rate, in CHL cells. Xanthone inhibited the genotoxic effects of PQ and NaNO_2 at concentrations of more than 5μM. The present results suggested the potent antigenotoxic effects of xanthones in mangosteens.
- 日本トキシコロジー学会の論文
- 2007-12-14
著者
-
TANAKA Reiko
Department of Infections, Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba Univer
-
Tanaka Reiko
Department Of Nursing Akita University Of Nursing And Welfare
-
Tanaka Reiko
Department Of Endocrine Surgery Tokyo Women's Medical College
関連論文
- Characteristics of 17 Paracoccidioides brasiliensis isolates
- The Adsorption of NO on Various Metal Tape-Porphyrins : A First-Principles Study(Condensed matter: electronic structure and electrical, magnetic, and optical properties)
- Osteopontin Expression May Be Induced by c-Src in Papillary Thyroid Carcinoma
- STUDY ON THE ABSORPTION AND PROTEIN BINDING OF CARBARYL, DIELDRIN AND PARAQUAT IN RATS FED ON PROTEIN DIET
- DISTRIBUTION AND BILIARY EXCRETION OF CARBARYL, DIELDRIN AND PARAQUAT IN RATS : EFFECT OF DIETS
- INHIBITORY EFFECTS OF XANTHONE ON PARAQUAT- AND NaNO_2-INDUCED GENOTOXICITY IN CULTURED CELLS
- HEMOLYTIC EFFECTS AND BINDING BY ERYTHROCYTES OF BENZYL ALCOHOL (The Fourth Meeting for the Study of Toxic Effect)
- 102. Deformation of Surface Structure of Erythrocytes Induced by Mercurials (The Second Meeting for the Study of Toxic Effect)
- INDUCTION OF A SISTER-CHROMATI]D EXCHANGE BY NITROGEN OXIDES AND ITS PREVENTION BY SOD
- Primary Hyperparathyroidism Associatiated with Aldosterone-Producing Adrenocortical Adenoma and Breast Cancer : Relation to MEN1 Gene
- STIMULATION AND INHIBITION OF DNA SYNTHESIS AND CELL GROWTH BY PARAQUAT IN CULTURED CELLS
- Protective Effects of (-)Epigallocatechin Gallate and (+)Catechin on Nitrogen Oxide-Induced Sister Chromatid Exchange
- A Relative High Dose of Vitamin E Does Not Attenuate Unweighting-Induced Oxidative Stress and Ubiquitination in Rat Skeletal Muscle
- Decision Making Using Postoperative CEA and CA 15-3 for Detection of Breast Cancer Recurrence
- HEMOLYSIS AND MORPHOLOGICAL CHANGES IN RAT ERYTHROCYTES WITH MERCURIALS
- EFFECT OF MERCURIALS ON THE MEMBRANE PROTEIN OF RAT ERYTHROCYTES
- EFFECT OF BENZYL ALCOHOL ON ADENOSINE TRIPHOSPHATASE, p-NITROPHENYLPHOSPHATASE AND ACETYLCHOLINESTERASE IN RAT ERYTHROCYTE MEMBRANE
- Larva of Chascanopsetta lugubris lugubris (Bothidae) disgorged by a lancetfish (Alepisaurus sp.)
- EFFECTS OF PENTOXIFYLLINE ON ACTIVE OXYGEN-INDUCED SISTER-CHROMATID EXCHANGE
- EFFECT OF CAPTOPRIL, A CONVERTING ENZYME INHIBITOR ON RENAL VASCULAR RESISTANCE IN PENTOBARBITAL ANESTHETIZED DOGS
- Hypotensive effect of captopril, an angiotensin converting enzyme inhibitor in pentobarbital anesthetized dogs.