高分解マイクロ波誘電分光による筋肉タンパク周りの水の回転運動特性と筋肉収縮の分子メカニズム(<ミニ特集>「生物物理」におけるタンパク質ダイナミクス測定)

概要

論文の詳細を見る
A precision microwave dielectric spectroscopic technique has been developed. This technique enables us to analyze hydration properties of ions, proteins, and other biomolecules. φ-scan method gives an image of the information of spatial distribution of dielectric property of water surrounding protein molecules. Fixed φ analysis gives a direct comparison of hydration properties of different proteins. With this technique we analyzed the state change of F-actin hydration upon binding with myosin, and found that hyper-mobile water (HMW) is induced around F-actin and increased upon binding with myosin S1. Thus, we may obtain further information of collective properties of water surrounding proteins and biomolecules.
日本生物物理学会の論文
2007-09-25