A Case of Acute Organotin Poisoning
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概要
- 論文の詳細を見る
Alkyl compounds of tin chlorides are widely used for the production of plastics in the chemical industry. They inhibit the dissociation of hydrochloric acid from polyvinyl chloride (PVC) and in combination with PVC they are not toxic. However, as free molecules, organic tin compounds are highly toxic in contrast to inorganic tin compounds. The toxic components are dimethyltin chloride and trimethyltin chloride. Previous studies have reported that dimethyltin chloride is toxic to the liver and kidneys, whereas trimethyltin chloride damages the central nervous system. The neurotoxicity of dialkyltin or trialkyltin compounds has been recognized in animal studies, but only a few descriptions of their human toxicity have been reported. Especially, reports of human dimethyltin intoxication are vert rare. We report here a case with neurological manifestations similar to trialkyltin encephalopathy from the exposure to dimethyltin compounds.
- 社団法人日本産業衛生学会の論文
著者
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KIM Yu
Department of Pulmonary and Critical Care Medicine, Gachon University, Gil Medical Center
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Kim Yangho
Department Of Occupational And Environmental Medicine Ulsan University Hospital University Of Ulsan
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Kim Yangho
Department Of Occupational And Environmental Medicine Ulsan University Hospital
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Endo Yoko
Research Center for Occupational Poisoning, Tokyo Rosai Hospital
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Yoo Cheol
Department Of Occupational And Environmental Medicine Ulsan University Hospital University Of Ulsan
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Jeong Kyoung
Department Of Occupational And Environmental Medicine Ulsan University Hospital University Of Ulsan
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SIM Chang
Department of Occupational and Environmental Medicine, Ulsan University Hospital, UDepartment of Occ
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CHOY Nari
Department of Occupational and Environmental Medicine, Ulsan University Hospital, UDepartment of Occ
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KIM Jongchul
Department of Neurology, Ulsan University Hospital, University of Ulsan College of Medicine
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EUM Jun
Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine
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NAKAJIMA Yoshiaki
Research Center for Occupational Poisoning, Tokyo Rosai Hospital
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Endo Yoko
Research Center For Occupational Poisoning Tokyo Rosai Hospital
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Kim Yu
Department Of Internal Medicine Institute Of Gastroenterology Yonsei University College Of Medicine
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Eum Jun
Department Of Internal Medicine Ulsan University Hospital University Of Ulsan College Of Medicine
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Choy Nari
Department Of Occupational And Environmental Medicine Ulsan University Hospital Udepartment Of Occup
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Sim Chang
Department Of Occupational And Environmental Medicine Ulsan University Hospital Udepartment Of Occup
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Kim Jongchul
Department Of Neurology Ulsan University Hospital University Of Ulsan College Of Medicine
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Endo Yoko
Research Center For Occupational Poisoning Kansai Rosai Hospital Japan Labour Health And Welfare Org
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Nakajima Yoshiaki
Research Center For Occupational Poisoning Tokyo Rosai Hospital
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Kim Yu
Department Of Biochemistry College Of Science Protein Network Research Center Yonsei University
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