The Structures of a β-Galactosidase Inhibitor, Galactostatin, and Its Derivatives(Organic Chemistry)

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概要

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• The structure of the β-galactosidase inhibitor, galactostatin, isolated from Streptomyces lydicus PA-5726 was determined to be 5-amino-5-deoxygalactopyranose, in which the ring oxygen of galactose has been replaced by nitrogen. For this study, two derivatives of galactostatin were prepared by oxidation and reduction, respectively. The oxidation product of galactostatin was 5-amino-5-deoxygalactonic-δ-lactam (galactostatin-lactam) and the reduction product was 5-amino-1,5-dideoxygalactopyranose (1-deoxygalactostatin).

• 社団法人日本農芸化学会の論文
• 1988-03-23

著者

• Miyake Yukio

  Shionogi Research Laboratories Shionogi & Co. Ltd.

• EBATA Mitsuo

  Shionogi Research Laboratories, Shionogi & Co., Ltd.

• Ebata Mitsuo

  Shionogi Research Laboratories Shionogi & Co. Ltd.

関連論文

• Isolation and Properties of a New β-Galactosidase Inhibitor, Galactostatin, from Streptomyces lydicus(Microbiology & Fermentation Industry)
• The Structures of a β-Galactosidase Inhibitor, Galactostatin, and Its Derivatives(Organic Chemistry)
• Inhibition of β-Galactosidase by Galactostatin, Galactostatin-lactam, and 1-Deoxygalactostatin(Biological Chemistry)

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