Relationship Between Regional and Global Left Ventricular Systolic and Diastolic Function in Patients With Coronary Artery Disease Assessed by Strain Rate Imaging

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概要

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• Background The relationship between regional and global left ventricular function has not been evaluated. The present study aimed to assess whether regional myocardial contraction and relaxation reflect global left ventricular systolic and early diastolic function, respectively. Methods and Results The study involved 45 patients with coronary artery disease (CAD). Conventional echocardiography was performed, and segmental peak strain rate (SR) in the systole (SSR) and early diastole (ESR) were obtained from tissue Doppler imaging in each of 18 segments of the left ventricular myocardium from the apical views. The ESR was significantly correlated with SSR in all studied segments (r=0.55, p<0.0001). The average values of SR indices in each patient were defined as SSR index and ESR index, which were derived by dividing the summed value of the SSR or ESR by the number of respective assessable segments. A significant positive relationship was observed between the SSR index and left ventricular ejection fraction (r=0.85, p<0.0001). Also, there was a positive correlation between the ESR index and mitral flow E (r=0.68, p<0.0001). Conclusions Regional myocardial contraction and relaxation, as assessed by SR imaging, were closely related in patients with CAD. Furthermore, regional myocardial contraction and relaxation are important factors affecting global left ventricular systolic and early diastolic function.

• 社団法人日本循環器学会の論文
• 2007-03-20

著者

• YOKOYAMA Mitsuhiro

  Division of Cardiovascular and Respiratory Medicine, Department of Internal Medicine, Kobe Universit

• Yokoyama Mitsuhiro

  Division Of Cardiovascular And Respiratory Medicine Department Of Internal Medicine Kobe University

• Kawai Hiroya

  Division of Cardiovascular and Respiratory Medicine Department of Internal Medicine, Kobe University

• ONISHI Tetsuari

  Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate Schoo

• Tatsumi Kazuhiro

  Division of Cardiovascular Medicine, Kobe University Graduate School of Medicine

• Kataoka Toshiya

  Department of Cardiovascular Medicine, Kobe University Graduate School of Medicine

• Tanaka Hidekazu

  Division Of Cardiovascular And Respiratory Medicine Kobe University Graduate School Of Medicine

• Kataoka Toshiya

  Division of Cardiovascular Medicine, Kobe University Graduate School of Medicine

• Nose Takahisa

  Division of Cardiovascular and Respiratory Medicine, Department of Internal Medicine, Kobe Universit

• Mizoguchi Takahiro

  Division of Cardiovascular and Respiratory Medicine, Department of Internal Medicine, Kobe Universit

• Ohnishi Tetsuari

  Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School

• Kataoka Toshiya

  Department Of Cardiovascular Medicine Kobe University Graduate School Of Medicine

• Tatsumi Kazuhiro

  Division Of Cardiovascular Medicine Kobe University Graduate School Of Medicine

• Onishi Tetsuari

  Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School

• Nose Takahisa

  Division Of Cardiovascular And Respiratory Medicine Department Of Internal Medicine Kobe University

• Mizoguchi Takahiro

  Division Of Cardiovascular And Respiratory Medicine Department Of Internal Medicine Kobe University

• Kawai Hiroya

  Division Of Cardiovascular And Respiratory Medicine Department Of Internal Medicine Kobe University

• Kawai Hiroya

  Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School

• Kumagai Hiroyuki

  Department Of Cardiovascular And Respiratory Medicine Kobe University Graduate School Of Medicine

• Kumagai Hiroyuki

  Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School

• Tatsumi Kazuhiro

  Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School

• Kawai Hiroya

  Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School

• Onishi Tetsuari

  Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School

• Kumagai Hiroyuki

  Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School

• Onishi Tetsuari

  Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School

• Tanaka Hidekazu

  Division Of Bio-system Pharmacology Department Of Pharmacology Graduate School Of Medicine Osaka Uni

• Kumagai Hiroyuki

  Department Of Internal Medicine Division Of Cardiovascular Medicine Kobe University Graduate School Of Medicine

• Onishi Tetsuari

  Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School Of Medicine

• Kawai Hiroya

  Division of Cardiology, Himeji Cardiovascular Center

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