Neurite Outgrowths of Neurons with Neurotrophin-Coated Carbon Nanotubes(CELL AND TISSUE ENGINEERING)

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概要

• 論文の詳細を見る

• Multiwalled carbon nanotubes(CNTs) coated with neurotrophin were used to regulate the differentiation and survival of neurons. Neurotrophin(nerve growth factor [NGF] or brain-derived neurotrophic factor [BDNF]) was covalently bound to CNTs modified by amino groups using a 1-ethyl-3-(3-dimethylaminopropyi) carbodiimide hydrochloride(EDC) reagent. The CNTs coatedwith NGF or BDNF promoted the neurite outgrowths of neurons in the same manner as soluble NGF and soluble BDNF. By enzyme-linked immunosorbent assay(ELISA), we demonstrated that neurotrophin-coated CNTs carry neurotrophin. These results suggest that neurotrophin-coated CNTs have biological activity and stimulate the neurite outgrowths of neurons.

• 社団法人日本生物工学会の論文
• 2007-03-25

著者

• Kitazawa Ayako

  Bio-Nano Electronics Research Center, Toyo University

• Naka Yukie

  Bio-Nano Electronics Research Center, Toyo University

• Whitby Raymond

  School Of Pharmacy And Biomolecular Sciences University Of Brighton

• Naka Yukie

  Bio-nano Electronics Research Center Toyo University

• Kitazawa Ayako

  Graduate School Of Life Sciences Toyo Univ.

• Kitazawa Ayako

  Bio-nano Electronics Research Center Toyo University

• Matsumoto Kotaro

  Faculty of Life Sciences, Toyo University

• Sato Chie

  Faculty of Life Sciences, Toyo University

• Naka Yukie

  Graduate School of Life Sciences, Toyo University

• Shimizu Norio

  Faculty of Life Sciences, Toyo University

• Shimizu Norio

  Bio-nano Electronics Research Center Toyo University:graduate School Of Life Sciences Toyo Universit

• Sato Chie

  Faculty Of Life Sciences Toyo University

• Matsumoto Kotaro

  Faculty Of Life Sciences Toyo University

• Shimizu Norio

  Faculty Of Life Sciences Toyo University

関連論文

• Accumulation of neurons differentiated from mouse embryonic stem cells in particular areas of culture plate surface(CELL AND TISSUE ENGINEERING)
• Neurite Outgrowths of Neurons with Neurotrophin-Coated Carbon Nanotubes(CELL AND TISSUE ENGINEERING)
• Neurite Outgrowths of Neurons Using Neurotrophin-Coated Nanoscale Magnetic Beads(MEDICAL BIOTECHNOLOGY)
• Neurite Outgrowths of Neurons on Patterned Self-Assembled Monolayers(MEDICAL BIOTECHNOLOGY)
• Production of Brain-Derived Neurotrophic Factor in Escherichia coli by Coexpression of Dsb Proteins(Microbiology & Fermentation Technology)
• Differentiation of Mouse Embryonic Stem Cells into Neurons Using Conditioned Medium of Dorsal Root Ganglia(MEDICAL BIOTECHNOLOGY, Advances in Biomedical Science and Engineering)
• Characterization of Neurons Differentiated from Mouse Embryonic Stem Cells Using Conditioned Medium of Dorsal Root Ganglia(CELL AND TISSUE ENGINEERING)

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