Two Minor Diterpene Glycosides and an Eudesman Sesquiterpene from Coleus forskohlii
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概要
- 論文の詳細を見る
Two new labdane diterpene glycosides, forskoditerpenosides A, B (1, 2) and a new eudesmane sesquiterpene, 4β, 7β, 11-enantioeudesmantriol (3), were isolated from the ethanol extract of the whole plant of Coleus forskohlii. Their structures and stereochemistry were elucidated by extensive spectroscopic analysis and chemical methods. The structure of compound 3 was confirmed by X-ray diffraction. This is the first report about the occurrence of glycosides derived from the kind of labdane diterpene, 8, 13-epoxy-labd-14-en-11-one, in the nature. Compounds 1 and 2 showed relaxative effects on isolated guinea pig tracheal spirals in vitro.
- 公益社団法人日本薬学会の論文
- 2007-03-01
著者
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Zhou Xiang
Department Of Medical Genetics Zhongshan Medical College Sun Yat-sen University
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Zhou Xiang
Department Of Natural Medicinal Chemistry China Pharmaceutical University
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Zhou Xiang
Department Of Cardiovascular Surgery Juntendo University Hospital
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NIWA Masatake
Faculty of Pharmacy, Meijo University
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Niwa Masatake
Faculty Of Pharmacy Meijo University
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Niwa M
Faculty Of Pharmacy Meijo University
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Niwa Masatake
Fac. Of Pharmacy Meijo Univ.
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SHAN Yupei
Department of Natural Medicinal Chemistry, China Pharmaceutical University
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WANG Xiaobing
Department of Natural Medicinal Chemistry, China Pharmaceutical University
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KONG Lingyi
Department of Natural Medicinal Chemistry, China Pharmaceutical University
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Shan Yupei
Department Of Natural Medicinal Chemistry China Pharmaceutical University
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Kong Lingyi
Department Of Natural Medicinal Chemistry China Pharmaceutical University
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Wang Xiaobing
Department Of Natural Medicinal Chemistry China Pharmaceutical University
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Zhou Xiang
Department of Cardiology, The Second Affiliated Hospital of Soochow University, China
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