NaFを投与したラットにおける歯周組織の組織化学的研究

概要

論文の詳細を見る
The effects of fluoride on the enzyme activities of the periodontal tissues of rats, that received either 50 ppm NaF or 100 ppm NaF in the drinking water for a year, were investigated histochemically. The activities of the enzymes studied were alkaline phosphatase, acid phosphatase and β-glucuronidase. 1. Alkaline phosphatase activity decreased in the periodontal tissues of both NaF 50 ppm and NaF 100 ppm groups, as compared with that of the control group. There was little difference in acid phosphatase activity among the periodontal tissues of the three groups (the control, NaF 50 ppm and NaF 100 ppm groups). The activity of β-glucuronidase almost disappered in the periodontal tissues of both NaF 50 ppm and 100 NaF ppm groups, whereas the marked activity of the same enzyme was recognized in the periodontal tissues of the control group. 2. Alkaline phosphatase activity decreased in the bone of the body of the maxilla of both NaF 50 ppm and NaF 100 ppm groups, as compared with that of the control group. Acid phosphatase activity in the bone of the body of the maxilla was almost the same in both control and NaF 50 ppm groups, but the activity decreased in the similar area of NaF 100 ppm group.
特定非営利活動法人日本歯周病学会の論文
1979-03-28