Significance of Bone Marrow Stromal Cells in Hematopoiesis and Hematological Disorders
スポンサーリンク
概要
- 論文の詳細を見る
Bone marrow stromal cells (SC) play a crucial role in sustaining proliferation, differentiation and self-renewal of hematopoietic stem cells. It is quite possible that adherent cell layers derived from bone marrow support hematopoiesis in liquid culture (21). Bone marrow SC consist of various types of cells, with fibroblasts (FB) as one of the main components. In the last several years, many laboratories have performed detailed analyses of the regulatory role of SC in hematopoiesis using long-term liquid cultures and semi-solid colony assays. In this review, the author summarizes and discusses characteristics of SC, especially FB; their hematopoietic stimulatory and inhibitory effects; and their significance in hematological disorders.
- 東海大学の論文
著者
-
NAGAO Tadami
The Fourth Department of Internal Medicine, School of Medicine, Tokai University
-
Nagao Tadami
The Fourth Department Of Internal Medicine School Of Medicine Tokai University
関連論文
- Nodular Sclerosing Hodgkin's Disease with Massave Skin Invasion
- Evaluation of Cefmetazole and Piperacillin with or without Tobramycin for Infections in Patients with Hematological Disorders
- Chemoimmunotherapy with Krestin in Acute Leukemia
- Human Bone Marrow Contains Fibroblast Colony Forming Cells
- Bone Marrow Fibroblasts-Conditioned Medium Regulates the Proliferation of Leukemic Cells
- Small-dose Cytosine Arabinoside in the Treatment of Elderly Patients with Acute Leukemia and Refractory Anemia with Excess of Blast
- The Effect of Bestatin on Patients with Acute and Chronic Leukemia and Malignant Lymphoma
- Prognostic Factors in Adult Patients with Acute Leukemia
- Abnormal Regulation of Granulopoiesis by Bone Marrow Fibroblasts in Leukemia
- Characteristics of Bone Marrow Fibroblasts and their Significance in Hematopoiesis
- Pathogenesis of Aplastic Anemia
- Significance of Bone Marrow Stromal Cells in Hematopoiesis and Hematological Disorders
- Essential Thrombocythemia Developing into Refractory Anemia and Complicated by Acute Myeloid Leukemia
- Acquisition of CD13 and CD33 Expression at Relapse on Acute Myeloid Leukemia Cells with an Unusual Phenotype: MPO+CD13-CD33-.
- Thymic Carcinoma Associated with Pinealoma and Terminating with Peroxidase-negative Acute Myeloid Leukemia.