Measurement of Functional Residual Capacity and Pulmonary Carbon Monoxide Diffusing Capacity during Mechanical Ventilation with PEEP

概要

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First, our new simplified method to measure FRC and D_<Lco> simultaneously during mechanical ventilation was described in detail. Secondly, we applied the method to ARDS patients and observed the effects of PEEP on arterial blood gases (ABGs), FRC and D_<Lco> of these patients. As reported hitherto, FRC was consistently increased by PEEP, whereas ABGs in some cases were not necesserily improved with increase in FRC. D_<Lco>/FRC remained unchanged, although D_<Lco> increased with PEEP. We concluded that the dissociation of FRC and ABG data in a group of patients could be caused by wasted ventilation which might be attributed to V_A/Q uneveness.
東海大学の論文