基本研究の展開 : 突然変異説のアンチテーゼから進化医学の創造へ : ストレス状態によるヒト遺伝子構造の変動調節機能の発見(研究紹介 : 環境影響生化学その1)

概要

論文の詳細を見る
We previously found that in human cells, interferons suppress mutagenic events, possibly via protease activation. Based on this finding we evaluated the physiological functions that supervise the frequency of genetic mutation. The functions seem to be regulated by serum factors such as cytokines in the human body. The factors induce the above protease activation, which may regulate intracellular chaperones' metabolism. Then the chaperones may interact with molecules that modify DNA structures. This research is covering various other problems, related to gerontology, space science, smoking research, water science, and other fields. Eventually, Evolutionary medicine will be created.
千葉大学の論文
2005-10-01