MODIFICATION OF PEA OLFACTORY FUNCTION TEST : A COMPARATIVE STUDY WITH UPSIT AND T&T OLFACTOMETER

概要

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Smell dysfunction is evaluated using olfactory function tests. However, an easy and reliable test has not yet been developed. By employing the advantage of the PEA (phenyl ethyl alcohol) test and the T&T Olfactometer, we developed a conventional olfactory function test we have named the modified PEA test. We used commercially available (3-PEA as an odorant, which consisted of eight different concentrations ranging from -7.2 log to -0.2 log concentration. The test was performed by a forced choice method. Olfactory function was evaluated in 54 patients with smell dysfunction and in 86 healthy volunteers using the modified PEA test, UPSIT (University of Pennsylvania Smell Identification Test) and a T&T Olfactometer. Test-retest reliability and correlation coefficients among these tests were compared with one another. The modified PEA test showed high reproducibility and high sensitivity in the detection threshold of smell, and correlated well with the other olfactory function tests of UPSIT and the T&T Olfactometer. Moreover, olfactory disorders were able to be distinguished clearly from normal olfactory function. Because the modified PEA test uses ready-made odorant and takes only 5 minutes to perform, the tests can be used as an easy and reliable olfactory function test as well as a screening test for olfactory disorders.
名古屋市立大学の論文
2005-03-28