Caseous Necrotic Granuloma in the Pituitary Stalk Due to Nontuberculous Mycobacteria (Mycobacterium Tokaiense) Infection : Case Report
スポンサーリンク
概要
- 論文の詳細を見る
A 36-year-old man with no history of immunosuppression presented with diabetes insipidus, but no other hormonal disturbances. Magnetic resonance imaging of the brain revealed an enhanced mass in the pituitary stalk appearing as a thickened pituitary stalk. The mass lesion was completely removed through the right optico-carotid space. Histological examination showed epithelioid cell granuloma with caseous necrosis, which strongly suggested mycobacterial infection. However, acid-fast staining detected no bacteria. Polymerase chain reaction (PCR) examinations of the gastric juice and cerebrospinal fluid for tuberculosis were negative. Nested PCR and deoxyribonucleic acid (DNA) sequencing of the DNA from the surgical specimen disclosed Mycobacterium tokaiense DNA sequences. This rare case of pituitary stalk granuloma caused by M. tokaiense shows that if the surgical specimen contains caseous necrosis, nested PCR and DNA sequencing are useful methods to identify mycobacterial infection.
- 日本脳神経外科学会の論文
- 2006-02-15
著者
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NAKAO Yasuaki
Department of Neurosurgery, Juntendo University Shizuoka Hospital
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YAMAMOTO Takuji
Department of Neurosurgery, Juntendo University Shizuoka Hospital
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MORI Kentaro
Department of Neurosurgery, Juntendo University Shizuoka Hospital
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TAMURA Masaru
Mammalian Genetics Laboratory, Genetic Strains Research Center, National Institute of Genetics
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Tamura Masaru
Mammalian Genetics Lab. Genetic Strains Res. Center National Inst. Of Genetics
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森 健太郎
Department Of Neurosurgery Juntendo University Shizuoka Hospital
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Yamamoto Takuji
Department Of Neurosurgery Juntendo University Shizuoka Hospital
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MAEDA Minoru
Department of Neurosurgery, Juntendo University, Shizuoka Hospital
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KONDO Akihide
Department of Neurological Surgery, Juntendo University Urayasu Hospital
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Maeda Minoru
Department Of Neurosurgery Juntendo University Shizuoka Hospital
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IWATA Junko
Institute of Juntendo Casualty Center
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Mori Kentaro
Department Of Neurosurgery
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Kondo Akihide
Department Of Neurological Surgery Juntendo University Urayasu Hospital
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Kondo Akihide
Department Of Neurosurgery Juntendo University Shizuoka Hospital
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Tamura Masaru
Mammalian Genetics Laboratory National Institute Of Genetics
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Nakao Yasuaki
Department Of Neurosurgery Juntendo University Shizuoka Hospital
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Nakao Yasuaki
Department Of Neurosurgery Juntendo University School Of Medicine
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Mori Kentaro
Department Of Functional Polymer Science Shinshu University
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Maeda Minoru
Department Of Neurosurgery
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Maeda Minoru
Department Of Chemistry Faculty Of Engineering Science Osaka University
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Mori Kentaro
Department of Cell Biology, Institute of Development, Aging and Cancer Tohoku University
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YAMAMOTO Takuji
Department of Neurosurgery, Juntendo University, Shizuoka Hospital
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Yamamoto Takuji
Department of Electrical and Electronics Engineering, Nippon Institute of Technology, Miyashiro, Saitama 345-8501, Japan
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Maeda Minoru
Department of Biomolecular Recognition Chemistry, Graduate School of Pharmaceutical Sciences, Kyushu University
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