赤血球の形状がおよぼす光散乱現象の検討(OS.13 溶液・分散系のマイクロ・ナノ構造と流れの相互作用)

概要

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One of the causes of micro thrombosis is thought to be erythrocyte deformability. In particularly, the erythrocytes might become irreversible configuration (lower deformability) prior to lysis because erythrocytes in cardiopulmonary devices were subjected to unphysiological level of mechanical stress. Therefore, it is important for development of cardiopulmonary devices to investigate the relationship between erythrocyte configuration and deformability. The purpose of this study is to investigate the relationship between erythrocyte deformability and light scattering density. At first, we investigated the relationship between erythrocyte configuration and light scattering density. An estimation of experimental apparatus was applied to numerical analysis of differential cross-section (Mie single phase function theory) and to measure light scattering intensity of sphere particles. The differential cross-section of blood sample is similar to the scattering cross-section of sphere. However, the differential cross-section of blood sample did not find the dimple. In conclusion, we could measure erythrocyte of phase function by using our experimental apparatus.
社団法人日本機械学会の論文
2004-03-03