Protection of Post-infarct Remodeled Myocardium by Erythropoietin is Induced by a PI3K/Akt-independent and Mitochondrial K_<ATP> Channel-dependent Mechanism(Myocardial Ischemia-reperfusion, Basic 2 (IHD), The 69th Annual Scientific Meeting of the Japanese

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概要

• 論文の詳細を見る
• 社団法人日本循環器学会の論文
• 2005-03-01

著者

• Shimamoto Kazuaki

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• 坂本 淳

  札幌医科大学第二内科

• MIURA Tetsuji

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• Miki Takayuki

  Second Department of Internal Medicine, Sapporo Medical University

• Naitoh Kazuyuki

  Second Department of Internal medicine, Sapporo Medical University

• Yano Toshiyuki

  Second Department of Internal medicine, Sapporo Medical University

• Nishihara Masahiro

  Second Department of Internal Medicine, Sapporo Medical University

• Sakamoto Jun

  Second Department of Internal Medicine, Sapporo Medical University

• Kobayashi Hironori

  Second Department of Internal Medicine, Sapporo Medical University

• Miki Takayuki

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Miura Tetsuji

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Miura Tetsuji

  Second Department Of Internal Medicine Department Of Clinical Laboratory Medicine Sapporo Medical Un

• Naitoh Kazuyuki

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Nishihara Masahiro

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Shimamoto Kazuaki

  Second Department Of Internal Medicine (cardiovascular Medicine) Sapporo Medical University School O

• Sakamoto Jun

  Second Department Of Internal Medicine Sapporo Medical University

• Sakamoto Jun

  Department Of Pharmacology School Of Medicine Sapporo Medical University

• Yano Toshiyuki

  Second Department Of Medicine Sapporo Medical University School Of Medicine

• Kobayashi Hironori

  Second Department Of Internal Medicine Sapporo Medical University

関連論文

• PJ-001 FFT and Electrophysiological Analyses of Spatial Inhomogeneity of the Remodeled Left Atrium And Pulmonary Venous Ostium in Chronic Atrial Fibrillation(Arrhythmia, Diagnosis/Pathophysiology/EPS 3 (A) : PJ1)(Poster Session (Japanese))
• A Promoter Polymorphism of Lamin A/C Gene is an Independent Genetic Predisposition to Arterial Stiffness in a Japanese General Population (The Tanno and Sobetsu Study)
• PE-099 Insulin Resistance in Adolescence is Induced by Angiotensin II Infusion in Prepuberty via Inflammatory Cytokines.(Hypertension, basic(02)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• FRS-094 Difference in the Cut-off Point of Extibated GFR as a Predictor of Cardiovascular Event between Elderly and Non-elderly People(Renal Dysfunction and Cardiovascular Disease(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japa
• 3 Significance of adiponectin and adipocyte fatty acid binding protein as biomarkers of cardiovascular diseases and insulin sensitivity(Biomarkers in cardiovascular diseases,Roundtable Discussion 4 (RT-04) (H),Special Program,The 72nd Annual Scientific Me
• Quadricuspid aortic valve associated with aortic stenosis and regurgitation : report of a case and a review of the literature
• Visceral Obesity in Japanese Patients with Metabolic Syndrome : Reappraisal of Diagnostic Criteria by CT Scan
• PJ-642 A Polymorphism in Promoter Region of CYP4A11 Gene is Associated with a New Onset of Hypertension : the Tanno-Sobetsu Study(Hypertension, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Noninvasive Assessment of Left Atrial Function by Strain Rate Imaging in Patients with Hypertension : A Possible Beneficial Effect of Renin-Angiotensin System Inhibition on Left Atrial Function
• Effects of Angiotensin II Type 1 Receptor Gene Polymorphisms on Insulin Resistance in a Japanese General Population : The Tanno-Sobetsu Study
• Olmesartan Is an Angiotensin II Receptor Blocker with an Inhibitory Effect on Angiotensin-Converting Enzyme
• Persistent Insulin-Sensitizing Effects of Sarpogrelate Hydrochloride, a Serotonin 2A Receptor Antagonist, in Patients With Peripheral Arterial Disease
• Long-Term Outcome of Implanted Cardioverter Defibrillators in Survivors of Out-of-Hospital Cardiac Arrest of Cardiac Origin
• FRS-094 Difference in the Cut-off Point of Extibated GFR as a Predictor of Cardiovascular Event between Elderly and Non-elderly People(Renal Dysfunction and Cardiovascular Disease(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japa
• 3 Significance of adiponectin and adipocyte fatty acid binding protein as biomarkers of cardiovascular diseases and insulin sensitivity(Biomarkers in cardiovascular diseases,Roundtable Discussion 4 (RT-04) (H),Special Program,The 72nd Annual Scientific Me
• FRS-094 Difference in the Cut-off Point of Extibated GFR as a Predictor of Cardiovascular Event between Elderly and Non-elderly People(Renal Dysfunction and Cardiovascular Disease(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japa
• 3 Significance of adiponectin and adipocyte fatty acid binding protein as biomarkers of cardiovascular diseases and insulin sensitivity(Biomarkers in cardiovascular diseases,Roundtable Discussion 4 (RT-04) (H),Special Program,The 72nd Annual Scientific Me
• Increased Serum Apolipoprotein B48 Concentration in Patients with Metabolic Syndrome
• PJ-632 Prognostic Value of Cardiac Sympathetic Nerve Activity in Heart Failure Patients with Preserved Left Ventricular Ejection Fraction(PJ106,Nuclear Cardiology (Others) (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Ci
• PJ-623 Alterations in Intra-atrial Electromechanical Delay and Left Atrial Function in Healthy Overweight Subjects : A Study of Two-dimensional Speckle Tracking Imaging(PJ105,Echo/Doppler (Others) 2 (I),Poster Session (Japanese),The 73rd Annual Scientific
• PJ-353 Feasibility, Reproducibility and Clinical Impact of Measurements of Left Ventricular Ejection Fraction and Left Atrial Volume Using Real-time Three-dimensional Echocardiography(PJ060,Echo/Doppler (New Technology) 4 (I),Poster Session (Japanese),The
• DPJ-003 Risk Assessment with ST-elevation in Inferior Leads by Drug Load Examination in Patient with Brugada Syndrome(DPJ01,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 1 (A),Digital Poster Session (Japanese),The 73rd Annual Scientific Meeting of The
• OJ-219 Relationship between Left Ventricular Geometry and Systolic Function of Longitudinal, Radial and Circumferential Directions in Patients with Hypertension(OJ37,Echo/Doppler (Myocardium) (I),Oral Presentation (Japanese),The 73rd Annual Scientific Mee
• 4 On-going Japanese Clinical Trials for Hypertension II : Seeking for More Effective Pharmacological Treatment(ESC-JCS Joint Symposium (ESC-JCS Joint Symposium) (H) Evidence-Based Medical Treatment of Hypertension,Special Program,The 72nd Annual Scientifi
• Variation in OSBPL10 is associated with dyslipidemia
• Surveillance study for creating the national clinical database relating to ECG-gated myocardial perfusion SPECT of asymptomatic ischemic heart disease in patients with type-2 diabetes mellitus : J-ACCESS 2 study design
• The Optimal Target Blood Pressure for Antihypertensive Treatment in Japanese Elderly Patients with High-Risk Hypertension : A Subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) Trial
• Blood Pressure Control in Japanese Hypertensives with or without Type 2 Diabetes Mellitus
• OJ-139 Quantitative Assessment of Left Atrial Function in Patients with Paroxysmal Atrial Fibrillation by Two-dimensional Speckle Tracking Imaging(OJ24,Echo/Doppler (Others) (I),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japane
• OJ-113 Immediate Extracorporeal Cardiopulmonary Resuscitation can Provide Better Neurological Outcomes in Patients with Out-of-Hospital Cardiac Arrest(OJ19,Cardiopulmonary and Critical Care/ACLS (H),Oral Presentation (Japanese),The 73rd Annual Scientific
• PJ-896 Prognostic Value of Renal Function in Patients with Left Ventricular Systolic Dysfunction(Kidney / Renal circulation(08)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-603 Lead Defects in Patients with Implantable Cardioverter-Defibrillators during Long-Term Follow-up(Arrhythmia, therapy(21)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-544 Clinical implications of resting myocardial perfusion abnormality in patients with multiple coronary risk factors without significant coronary artery stenosis(Nuclear cardiology(09)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of
• PJ-156 Cardiac sympathetic nerve activity in heart failure patients with preserved ejection fraction: A long-term prospective prognostic study(Nuclear cardiology(07)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulatio
• OJ-265 Mild Hypothermia can Provide Better Long-Term Outcomes in Patients with Out-of-Hospital Cardiac Arrest(Emergency care/CPR(02)(H),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Response to : Noninvasive Assessment of Left Atrial Function by Strain Rate Imaging in Patients with Hypertension : A Possible Beneficial Effect of Renin-Angiotensin System Inhibition on Left Atrial Function
• PJ-547 Combined Assessment of Cardiac Sympathetic Nerve Activity and Myocardial Perfusion can Predict Lethal Cardiac Events in Patients with Dilated Cardiomyopathy(Nuclear cardiology-6, The 71st Annual Scientific Meeting of the Japanese Circulation Societ
• PJ-091 Assessment of Longitudinal, Radial and Circumferential Systolic and Diastolic Strain Rates and Dyssynchrony in Patients with Non-ischemic Dilated Cardiomyopathy(Echo/Doppler-13, The 71st Annual Scientific Meeting of the Japanese Circulation Society
• OJ-163 Re-degradation of Left Ventricular Function After Resuscitation May Become an Early Index of Neurological Recovery in Out-of-hospital Cardiac Arrest(Emergency care-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-076 Assessment of Left Ventricular and Left Atrial Function by Strain Rate Imaging in Diabetic Patients with and without Hypertension(Echo / Doppler-04, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Comparison of Long-Term Clinical Outcome After Sirolimus-Eluting Stent Implantation in Patients With and Without Hemodialysis
• PE-593 Role of 20-Hydroxyeicosatetraenoic Acid on Impaired Renal Hemodynamics in Fructose-fed Rats(Kidney/Renal circulation-3 (H) PE104,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• The Role of Renal Natriuretic and Depressor Systems in Insulin-Resistant Hypertensive Rats
• OJ-449 Electrophysiological Effects of Nifekalant against Atrial Flutter Reentrant Circuit : Relationship with the Right Atrial Anatomical Architecture by 2D/3D-intracardiac Echocardiography(Arrhythmia, Pharmacological Therapy 5 (A) : OJ55)(Oral Presentat
• Role of Adiponectin in Insulin-Resistant Hypertension and Atherosclerosis
• Chinese Medicine, Jiang-Tang-Ke-Li, Improves Insulin Resistance by Modulating Muscle Fiber Composition and Muscle Tumor Necrosis Factor-α in Fructose-Fed Rate
• The Effect of Tumor Necrosis Factor-α on Tissue Specificity and Selectivity to Insulin Signaling
• Studies on left main trunk related myocardial infarction
• Troponin T is closely related to myocardial perfusion and metabolic damages in patients presenting with chest pain in emergency room
• Detection of critical electrophysiological conduction pathway of superior vena cava - right atrial junction guided by three dimensional intracardiac echocardiography
• Fluctuation of ventricular repolarization abnormality can predict continuity of ventricular fibrillation induced by direct current shock in implanted cardioverter-defibrillator patients
• Gender-, tracer-, and stress mode-related differences in quantitative data derived from gated SPECT in a normal Japanese population
• Delayed Onset of Pulmonary Hypertension Associated With an Appetite Suppressant, Mazindol : A Case Report
• IS071 Infarct Size Limitation by Sodium-hydrogen Exhange Inhibition Requires Activation of Mitochondrial ATP-senstive K Channeles
• Long-Term Outcome After Primary Stenting Versus Balloon Angioplasty for Acute Myocardial Infarction : Five-year Follow-up of a Case-control Study
• Impaired Exercise-Related Myocardial Uptake of Technetium-99m-Tetrofosmin in Relation to Coronary Narrowing and Diabetic State : Assessment with Quantitative Single Photon Emission Computed Tomography
• Influence of Hypertension on the Incidence of Cardiovascular Disease in Two Rural Communities in Japan : The Tanno-Soubetsu Study
• Relationship between Visceral Fat and Cardiovascular Disease Risk Factors : The Tanno and Sobetsu Study
• Development and Progression of Atherosclerotic Disease in Relation to Insulin Resistance and Hyperinsulinemia
• Post-Challenge Hyperglycemia Results in Acceleration of Cardiovascular Morbidity(Diabetes/Obesity 8 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Adiponectin and Renal Function in Glucose Tolerance Impairment : The Tanno and Sobetsu Study(Preventive Medicine/Epidemiology/Education/Health Policy 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Angiotensin II Receptor Blocker Prevents Increased Arterial Stiffness in Patients With Essential Hypertension
• PE-247 Detection of Ischemia in Patients with Acute Chest Pain by using Resting and Subsequent ATP Stress 99mTc-Tetrofosmin Myocardial SPECT(Nuclear Cardiology 9 (I) : PE42)(Poster Session (English))
• OE-059 Acute and Chronic Effects of Angiotensin II Receptor Blocker on Pulse Wave Velocity in Essential Hypertensives(Hypertension, Clinical 1 (H) : OE8)(Oral Presentation (English))
• Right Bundle Branch Block and Coved-Type ST-Segment Elevation Mimicked by Acute Cholecystitis
• Relationship between Pulse Wave Velosity and Risk Factors in Community Based Epidemiological Study
• Hepatocyte Growth Factor and 24-Hour Ambulatory Blood Pressure Monitoring
• OJ-104 Connexin-43 Contributes to Pro-survival Akt/GSK-3β signaling And Cardimyocyte Protection in a Receptor-specifit Manner(Cell death, apoptosis/necrosis(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soci
• OJ-103 Role of Intra-mitochondrial GSK-3β in Bax Regulation And Antiapoptotic Resistance of Cardiomyocytes(Cell death, apoptosis/necrosis(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PE-268 Ischemic Preconditioning Modifies Interactions between Connexin43 and Protein Kinases during Myocardial Ischemia(Myocardial ischemia-reperfusion, basic/clinical-4 (IHD) PE45,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of
• OE-080 Role of GSK-3 β as a Crucial Determinant of Anti-infarct Tolerance of the Myocardium(Acute myocardial infarction, basic-1 (IHD) OE14,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• OE-026 Activation of ERK and Suppression of Calcineurin are Interacting Mechanisms of Cardioprotection Afforded by δ-opioid Receptor Activation(Myocardial ischemia-reperfusion, basic/clinical-1 (IHD) OE5,Oral Presentation (English),The 70th Anniversary An
• Activation of δ-Opioid Receptor Suppresses Myocardial Ischemic Injury by ERK Activation during the Early Phase of Ischemia(Acute Myocardial Infarction, Basic 1 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Activation of the δ-opioid Receptor Induces Phosphorylation of Connexin43 at Ser368 by PKC-ε and Reduces Myocardial Infarct Size(Myocardial Ischemia-reperfusion, Basic 3 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Erythropoietin Reduces Myocardial Ischemic Injury, but not Reperfusion Injury, Through Activation of the Pl3k/Akt Pathway(Myocardial Ischemia-reperfusion, Basic 1 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PE-069 Suppression of Border Zone Remodeling by G-CSF/M-CSF Treatment Improves Ventricular Function after Infarction(Acute Myocardial Infarction, Basic 3 (IHD) : PE12)(Poster Session (English))
• OE-080 Shedding of TNF-a by Activation of ADAM17 Contributes to Activation of Tyrosine Kinase-Mediated Pathway in Ischemic Preconditioning(Myocardial Ischemia-Reperfusion, Basic and Clinical 1 (IHD) : OE10)(Oral Presentation (English))
• OE-079 Suppression of Gap Junction Permeability Is a Mechanism of Cardioprotection Afforded by Activation of the Mitochondrial KATP Channel(Myocardial Ischemia-Reperfusion, Basic and Clinical 1 (IHD) : OE10)(Oral Presentation (English))
• OE-003 Mechanisms of Improvement in Post-infarct Ventricular Function by M-CSF in the rat : Increased Myocyte Regeneration vs. Modulation of Infarct Repair(Acute Myocardial Infarction, Basic 1 (IHD) : OE1)(Oral Presentation (English))
• FRS-084 Ischemia/Reperfusion Up-regulates Egr-1 Expression by an NO and ERK-mediated Mechanism in the Heart.(NO and Cardiovascular System (H) : FRS10)(Featured Research Session (English))
• Metaloprotease-Disintegrin Is Involved in Tyrosine Kinase-Mediated Signaling in Ischemic Preconditioning
• PE-545 Distinct Roles of FOXO Subtypes in SIRT1-mediated Mn-SOD Up-regulation under Oxidative Stress(PE091,Molecular Biology (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)
• DPE-012 Activation of SIRT1, a Histone/Protein Deacetylase, by Resveratrol Up-regulates MnSOD and Suppresses the Progression of Heart Failure(DPE02,Heart Failure, Basic (M),Digital Poster Session (English),The 73rd Annual Scientific Meeting of The Japanes
• Contribution of gap junction communication to myocardial necrosis during ischemia/reperfusion
• OJ-016 Assessment of Age-related Changes of Left Ventricular Function in Healthy Subjects : A Two-dimensional Speckle Tracking Imaging(Echo/Doppler-3 (I) OJ3,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circu
• OJ-015 Assessment of Left Ventricular Longitudinal, Radial and Circumferential Strain Rates in Patients with Hypertension : A Two-dimensional Speckle Tracking Imaging Study(Echo/Doppler-3 (I) OJ3,Oral Presentation (Japanese),The 70th Anniversary Annual Sc
• Valsartan in Elderly Isolated Systolic Hypertension (VALISH) Study : Rationale and Design
• Early Defibrillation and Circulatory Support Can Provide Better Long-Term Outcomes Through Favorable Neurological Recovery in Patients With Out-of-Hospital Cardiac Arrest of Cardiac Origin
• Association between senescence-related uncoupling protein 2 gene polymorphisms and abdominal obesity in Japanese subjects : The Tanno and Sobetsu study
• Endogenous Immunoreactive Ouabain-Like and Digoxin-Like Factors in Reduced Renal Mass Hypertensive Rats
• The Role of Renal Natriuretic Depressor Systems on Hypertensive Mechanisms in Reduced Renal Mass Hypertensive Rats
• Effects pf Cilnidipine on Muscle Fiber Composition, Capillary Density and Muscle Blood Flow in Fructose-Fed Rats
• Effects of the Chinese Medicine TSJN on Insulin Resistance and Hypertension in Fructose-Fed Rats
• OE-036 Roles of GSK-3 β in Myocardial Protection Afforded by Activation of the Mitochondrial K_ Channel(OE06,Myocardial Ischemia-reperfusion (Basic) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Soci
• OE-010 Distinct Roles of PKC ε and p38MAPK in Preconditioning-induced Modulation of Gap Junction Permeability during Ischemia(OE02,ACS/AMI (Basic) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• OE-008 Homodimeric Erythropoietin (EPO) Receptor Provokes More Potent and Distinct Cytoprotective Signaling Compared with Heterodimeric EPO-common-β Subunit Receptor in the Heart(OE02,ACS/AMI (Basic) (IHD),Oral Presentation (English),The 73rd Annual Scien
• FRS-044 ROS-mediated Enhancement of ANT-cyclophilin-D Interaction Underlies Reduced Anti-infarct Tolerance and Lost Response of Cardiomyocytes to Pro-survival Signaling in Hypertrophied Hearts(FRS9,Novel Mechanisms of Myocardial Ischemia (IHD),Featured Re
• PJ-005 Impairment of Myocardial Response to Erythropoietin-Induced Protection in Hypertensive Hypertrophied Hearts(Acute myocardial infarction, basic(02)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PE-333 Resveratrol, An Activator of Longevity Protein SIRT1, Suppresses Progression of Heart Failure Through SIRT1-mediated Cardiomyocyte Protection Against Oxidant Stress(Heart failure, basic(03)(M),Poster Session(English),The 72nd Annual Scientific Meet
• OE-309 Relationship of the Mitochondrial K_ Channel and GSK-3β in Enhancement of Myocardial Tolerance against Infarction(Myocardial ischemia/reperfusion, basic/clinical(01)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Jap

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