Antiinflammatory and Analgesic Activities of the Tissue Culture of Saussurea involucrata(Pharmacology)
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概要
- 論文の詳細を見る
The tissue culture of Saussurea involucrata (TCSauI) KAR. et KIR. was studied to determine its antiinflammatory and analgesic activities in experimental animals. Similar to wild S. involucrata, TCSauI at doses of 75-300mg/kg i.g. for 7d markedly inhibited hindpaw edema induced by carrageenin in rats, ear edema induced by dimethylbenzene, and increased capillary permeability in the mouse abdominal cavity induced by acetic acid. Moreover, TCSauI had inhibitory activities against the writhing reaction induced by acetic acid and the hot plate reaction in mice. The present study provided evidence first that TCSauI has antiinflammatory and analgesic activities, suggesting the potential of the tissue culture technique to substitute for wild S. involucrata in the pharmaceutical industry.
- 公益社団法人日本薬学会の論文
- 2005-09-01
著者
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Wu Chun
Department Of Pharmacognosy Faculty Of Pharmaceutical Sciences Nagoya City University
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Wu Chun
Department Of Pharmacology Shenyang Pharmaceutical University
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YU Hai
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu Univer
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Yu Hai
Department Of Pharmacology Shenyang Pharmaceutical University
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Jia Jing
Department Of Pharmacology Shenyang Pharmaceutical University
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LIU Wen
Department of Pharmacology, Shenyang Pharmaceutical University
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HAO Yue
Department of Pharmacology, Shenyang Pharmaceutical University
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ZHENG Jian
Department of Pharmacology, Shenyang Pharmaceutical University
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JI Yu
Department of Pharmacology, Shenyang Pharmaceutical University
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Zheng Jian
Department Of Pharmacology Shenyang Pharmaceutical University
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Hao Yue
Department Of Pharmacology Shenyang Pharmaceutical University
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Ji Yu
Department Of Pharmacology Shenyang Pharmaceutical University
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Zheng Jian
Department Of Applied Mathematics Tsing Hua University
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Wu Chun
Department Of Electrical Engineering National Sun Yat-sen University
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Yu Hai
Department Of Food Engineering Tokyo University Of Fisheries
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Liu Wen
Department Of Chemistry Jinan University
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Wu Chun
Department Of Applied Molecular Bioscience Graduate School Of Bioagricultural Sciences Nagoya Univer
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Liu Wen
Department Of Pharmacology Shenyang Pharmaceutical University
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JIA Jing
Department of Laboratory Animal Science, School of Basic Medical Sciences, Capital Medical University
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