Cytotoxic Limonoids from Brazilian Melia azedarach
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概要
- 論文の詳細を見る
Three new C-seco limonoids (1-3) and one new tetracyclic limonoid (4) were isolated from a methanol extract of the ripe fruits of Melia azedarach collected in Curitiba, Brazil, and their structures were elucidated by spectroscopic data analysis and comparison of spectral data with those of the previously known compounds. Among the limonoids isolated in the present study, compounds 3 and 4 exhibited significant inhibitory activity against HeLa S3 cancer cells, whereas 1 and 2 showed weak cytotoxicity.
- 公益社団法人日本薬学会の論文
- 2005-10-01
著者
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FUKUYAMA Yoshiyasu
Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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TAKAHASHI Hironobu
Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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Fukuyama Yoshiyasu
Institute Of Pharmacognosy Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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Fukuyama Yoshiyasu
Fac. Of Pharmaceutical Sciences Tokushima Bunri Univ.
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ZHOU Honglei
Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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HAMAZAKI Atsuko
Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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FONTANA Jose
LQBB-Department of Pharmacy, The Federal University of Paran
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WANDSCHEER Carolina
LQBB-Department of Pharmacy, The Federal University of Paran
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Zhou Honglei
Institute Of Pharmacognosy Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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Fontana Jose
Lqbb-department Of Pharmacy The Federal University Of Paran
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Hamazaki Atsuko
Institute Of Pharmacognosy Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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Takahashi Hironobu
Inst. Of Pharmacognosy Fac. Of Pharmaceutical Sciences Tokushima Bunri Univ.
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Wandscheer Carolina
Lqbb-department Of Pharmacy The Federal University Of Paran
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Takahashi Hironobu
Institute Of Pharmacognosy Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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