Studies on the Constituents of Juglans Species I : Structural Determination of (4S)- and (4R)-4-Hydroxy-α-tetralone Derivatives from the Fruit of Juglans mandshurica MAXIM. var. sieboldiana MAKINO
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概要
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Four enantiomerically pure new α-tetralones, (4S)- and (4R)-5-hydroxy-4-methoxy-α-tetralones and (4S)- and (4R)-5, 8-dihydroxy-4-methoxy-α-tetralones were isolated, together with five known ones, (4S)- and (4R)-4, 8-dihydroxy-α-tetralones, (4S)-4, 8-dihydroxy-5-methoxy-α-tetralone and (4S)- and (4R)-4-hydroxy-α-tetralones, from the fruit of Juglans mandshurica MAXIM. var. sieboldiana MAKINO. Their structures were established on the basis of spectral analysis. To the best of our knowledge, this is the first isolation of the (4R)-4-hydroxy-α-tetralone derivative from Juglans species.
- 公益社団法人日本薬学会の論文
- 2005-08-01
著者
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MACHIDA Koichi
Tohoku Pharmaceutical University
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KIKUCHI Masao
Tohoku Pharmaceutical University
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Kikuchi Masao
Tohoku College Of Pharmacy
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Kikuchi Masao
東北薬科大学
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MATSUOKA Erika
Tohoku Pharmaceutical University
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KASAHARA Takayuki
Tohoku Pharmaceutical University
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Machida Koichi
Tohoku College Of Pharmacy
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