Ceramide Constituents from Five Mushrooms
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概要
- 論文の詳細を見る
Five mushrooms, Panellus serotinus, Lyophyllum connatum, Amanita pantherina, Sarcodon aspratus and Lepista nuda, have been investigated chemically. Two new ceramides, (2S,3R,4E,8E)-N-hexadecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (1) and (2S,3R,4E,8E,9'Z,12'Z)-N-9',12'-octadecadienoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (2), have been isolated from Panellus serotinus. Compound 2 was also isolated from Lyophyllum connatum. Two new ceramides, (2S,2'R,3R,4E,8E)-N-2'-hydroxypentadecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (4) and (2S,2'R,3R,4E,8E)-N-2'-hydroxytetradecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (5), have been isolated from Amanita pantherina with (2S,2'R,3R,4E,8E)-N-2'-hydroxyhexadecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (3), a known synthetic compound. Compounds 3 and 4 were also isolated from Sarcodon aspratus and compound 3 was isolated from Lepista nuda. The structures of the new compounds were elucidated on the basis of their spectral data.
- 2002-05-01
著者
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YAOITA Yasunori
Tohoku Pharmaceutical University
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KOHATA Rie
Tohoku Pharmaceutical University
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KAKUDA Rie
Tohoku Pharmaceutical University
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MACHIDA Koichi
Tohoku Pharmaceutical University
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KIKUCHI Masao
Tohoku Pharmaceutical University
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Kakuda Rie
東北薬科大学
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Kikuchi M
東北薬科大学
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Kikuchi Masao
Tohoku College Of Pharmacy
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Machida Koichi
Tohoku College Of Pharmacy
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Yaoita Y
Tohoku Pharmaceutical University
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Yaoita Yasunori
Tohoku College Of Pharmacy
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