Simultaneous Comparison of Relative Reactivities of Twelve Major Anthocyanins in Bilberry towards Reactive Nitrogen Species
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概要
- 論文の詳細を見る
The reactivities of twelve major anthocyanins identified in bilberry extracts towards nitric oxide (NO・) and peroxynitrite (ONOO^-) were studied in vitro using capillary zone electrophoresis (CZE). The reactivities of the anthocyanins towards NO・ were slightly weak compared with that of (+)-catechin as a reference antioxidant under anaerobic conditions except delphinidin glycosides (Dp3glys). The reactivities of other anthocyanins were not significantly affected by either the aglycon structure or the type of sugar moiety. Under aerobic conditions, all anthocyanins and catechin showed significant enhancement of the reactivity, indicating that they reacted with other reactive species secondarily generated from NO・. Dp3glys showed rather extraordinally high reactivity towards ONOO^- compared to other anthocyanins which showed approximately two times low reactivity than catechin when compared with IC_<50>. Structural divergence in the reactivity was also small for all these anthocyanins.
- 公益社団法人日本薬学会の論文
- 2004-11-01
著者
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Matsugo Seiichi
Division Of Biotechnology Interdisciplinary Graduate School Of Medicine And Engineering University O
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ICHIYANAGI Takashi
Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences
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Matsuo Seiichi
Division Of Internal Medicine Nagoya University Graduate School Of Medicine
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Matsuo Seiichi
Division Of Clinical Immunology Department Of Medicine Nagoya University Graduate School Of Medicine
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HATANO Yoshihiko
Faculty of Applied Life Sciences, Niigata University of Pharmacy and Applied Life Sciences
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KONISHI Tetsuya
Faculty of Applied Life Sciences, Niigata University of Pharmacy and Applied Life Sciences
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Konishi T
Faculty Of Pharmaceutical Sciences Niigata University Of Pharmacy And Applied Life Sciences
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Hatano Yoshihiko
Faculty Of Pharmaceutical Sciences Niigata University Of Pharmacy And Applied Life Sciences
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Ichiyanagi Takashi
Faculty Of Applied Life Sciences Niigata University Of Pharmacy And Applied Life Sciences
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- Erratum: Simultaneous Comparison of Relative Reactivities of Twelve Major Anthocyanins in Bilberry towards Reactive Nitrogen Species [Chem. Pharm. Bull. 52(11): 1312-1315 (2004)]