Differential Kinetic Determination of Mixtures of Aniline and Its Derivatives Using N, N-Dimethyl-p-phenylenediamine
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The oxidative coupling reaction between the quinonediimine (QDI) of N, N-dimethyl-p-phenylenediamine (DMPD) and aromatic amines was utilized for the simultaneous determination of binary mixtures of aniline and its derivatives by the differential reaction rate method. A mixture of oxidant and DMPD was used instead of QDI because QDI was unstable. The effects of pH and the oxidant (K_3Fe (CN)_6,K_2Cr_2O_7 and their mixture) on the stability of the first oxidation product of DMPD, semiquinone (SQ), and on the equilibrium among DMPD, SQ and QDI, were investigated. The second-order rate constants of two amines reacting with QDI and the overall pseudo first-order rate constant of a mixture were determined from the slope of the straight line (the concentration of SQ vs. time) and by simplified complementary tristimulus colorimetry. Mixtures of amines down to 1.0×10^<-4>M were determined. Most relative errors were in the range of 0 to 14%. Among the compounds examined for interference, phenols and carbonyl compounds showed serious effects.
- 公益社団法人日本薬学会の論文
- 1980-07-25
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