スルホンアミド懸濁液のカチオン性界面活性剤による凝集, 分散, ケーキング

概要

論文の詳細を見る
Adsorption isotherms of a cationic surfactant, tetradecyltrimethylammonium bromide, on five kinds of sulfonamides, sulfadiazine, sulfaphenazole, sulfadimethoxine, sulfamonomethoxine, and sulfisomidine, from aqueous solution were determined at 30°. The isotherm of the surfactant on sulfisomidine illustrated a monolayer adsorption, and a multilayer adsorption on others. The amount adsorbed depended on the kind of sulfonamides, the amount adsorbed on sulfadiazine being the greatest and that for sulfisomidine the lowest. Further, it was suggested that both electrostatic and hydrophobic forces between sulfonamide and the surfactant were related to the adsorption. The porosity and redispersibility of a sedimentation bed depended not only on the amount adsorbed but also on the orientation of adsorbed molecules, and the relations between the amount adsorbed and porosity, and the amount adsorbed and redispersibility widely varied with the kind of sulfonamides. Especially, suspensions of sulfamonomethoxine showed a large specific sedimentation volume and easily redispersible sedimentation bed at all surfactant concentrations studied.
公益社団法人日本薬学会の論文
1974-02-25