スルホンアミド-水界面におけるカチオン性界面活性剤の配向とその懸濁液の分散性懸濁液のpHの吸着に対する影響

概要

論文の詳細を見る
Adsorption isotherms of hexadecyltrimethylammonium bromide on sulfaphenazole and sulfadiazine in aqueous solution were determined at pH 4.0 and 6.0,and at constant ionic strength and temperature. The ζ-potentials of these sulfonamides and porosity of the sedimentation bed of their suspension were also measured under the same conditions. It was found that ζ-potentials of both sulfaphenazole and sulfadiazine decrease as pH of suspensions increases. Changes in the surface charge of sulfaphenazole affect the adsorption of the surfactant on it and therefore the orientation of the surfactant molecules at water-sulfaphenazole interface and dispersibility of the suspensions vary with the pH change of the suspensions. In the case of adsorption on sulfadiazine, however, almost the same adsorption isotherms are obtained in the suspensions of pH 4.0 and 6.0. Some effects of the specific adsorption of anions have to be considered in addition to the effect of dissociating ions at the surface of both sulfonamides for their surface charge.
公益社団法人日本薬学会の論文
1974-12-25