菌類成分研究(第6報)Ergosterol-5,8-peroxideの生物活性について

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Ergosterol-5,8-peroxide (I) was isolated from a variation of Cercospora kikuchii obtained by irradiation with light. It showed potent cytotoxicity (IC_<50>=3.5 μg/ml) against mouse lymphemia L-1210/v/c in vitro, but exhibited no significant antitumor activity against both leukemia P-388 in CDF_1 mouse and sarcoma 180 in dd mouse. Peroxide I also did not affect on both gram-positive and gram-negative bacteria.
公益社団法人日本薬学会の論文
1982-04-25

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