Hepatoprotection by Human Epidermal Growth Factor (hEGF) against Experimental Hepatitis Induced by D-Galactosamine (D-GalN) or D-GalN/Lipopolysaccharide
スポンサーリンク
概要
- 論文の詳細を見る
The hepatoprotective effects of recombinant human epidermal growth factor (hEGF) on chemically and immunologically induced experimental liver injury models were examined. The hEGF clearly decreased serum transaminase levels in D-galactosamine (D-GalN) and D-GalN/lipopolysaccharide (LPS)-induced liver injury models under sub-lethal conditions. However, it has not significantly changed either serum or in vitro tumor necrosis factor (TNF)-α production or in vitro nitric oxide (NO) production, suggesting that the hepatoprotection by EGF is not mediated by inhibiting these pathological mediators produced in D-GalN and D-GalN/LPS-induced liver injury.
- 公益社団法人日本薬学会の論文
- 2000-10-01
著者
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Cho Jae
Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National Un
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Yeon Je
R & D Center Daewoong Pharmaceutical Co. Ltd.
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Pyo Mi
Ginsentology Research Laboratory And Department Of Physiology College Of Veterinary Medicine Konkuk
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Cho Jae
R & D Center Daewoong Pharmaceutical Co. Ltd.:department Of Immunology Windeyer Institute Of Med
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Cho J
College Of Engineering Institute Of Biotechnology Department Of Bioscience And Biotechnology Sejong
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Park Myung
R & D Center Daewoong Pharmaceutical Co. Ltd.
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YOO Eun
R & D Center, Daewoong Pharmaceutical Co., Ltd.
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PARK Myung
R & D Center, Daewoong Pharmaceutical Co., Ltd.
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YEON Je
R & D Center, Daewoong Pharmaceutical Co., Ltd.,
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KIM Jeom
R & D Center, Daewoong Pharmaceutical Co., Ltd.,
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YU Young
R & D Center, Daewoong Pharmaceutical Co., Ltd.,
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Cho Jae
Department Of Biomaterials Engineering College Of Bioscience And Biotechnology Kangwon National Univ
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Yu Y
R & D Center Daewoong Pharmaceutical Co. Ltd.
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Yoo Eun
R & D Center Daewoong Pharmaceutical Co. Ltd.
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Kim J
R & D Center Daewoong Pharmaceutical Co. Ltd.
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