Comparative Studies on Two Active Enzyme Forms of Human Urinary Urokinase. II. pH- and Heat-stabilities of Plasminogen Activator Activity

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概要

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• pH-stability curves and heat inactivation of the MW 55000 form (H-UK) and MW 36000 form (L-UK) of human urinary urokinase [EC 3. 4. 21. 31] were investigated by measurements of plasminogen activator activity. L-UK was distinctly more stable than H-UK (in terms of activity) on incubation at pH 6.8-9.6 or on heat treatment at temperatures above 60°. The ranges of pH 8.2-9.0 and 5-37°, were favorable for both H-UK and L-UK.

• 公益社団法人日本薬学会の論文
• 1981-02-25

著者

• 小畑 雄司

  Pharmaceuticals Research Center Kanebo Ltd.

• 鈴木 章

  Traditional Chinese Medicine Research Laboratory Kanebo Co. Ltd.

• 三羽 信比古

  Pharmaceuticals Research Center Kanebo Ltd.

• 鈴木 章

  Pharmaceuticals Research Center, Kanebo, Ltd.

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