Studies on the Preparation of Bioactive Lignans by Oxidative Coupling Reaction. III. Synthesis of Polyphenolic Benzofuran and Coumestan Derivatives by Oxidative Coupling Reaction of Methyl (E)-3-(4-Hydroxy-2-methoxyphenyl)propenoate and Their Inhibitory E
スポンサーリンク
概要
- 論文の詳細を見る
Three dihydrobenzofuran derivatives 11,19,22,a Pummere's ketone 20 and a dimeric phenylpropanoid 24 were synthesized by oxidative coupling reaction of methyl (E)-3-(4-hydroxy-2-methoxyphenyl)propenoate 10,which was prepared from umbelliferone. The major product 11 was converted into its acetate 21 and schizotenuin D analogs 27,28,29. A new coumestan derivative 13 was synthesized from 29. Ten synthetic compounds thus obtained were tested for inhibitory effects on lipid peroxidation in rat brain homogenate.
- 公益社団法人日本薬学会の論文
- 1994-12-15
著者
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野老山 喬
Faculty Of Science Osaka City University
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前田 四郎
New Drug Research Laboratories Kanebo Co. Ltd.
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増田 博史
Traditional Chinese Medicine Research Laboratories, Kanebo Co. Ltd.,
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増田 博史
Traditional Chinese Medicine Research Laboratories Kanebo Co. Ltd.
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Maeda S
New Drug Research Laboratories Kanebo Co. Ltd.
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- Studies on the Preparation of Bioactive Lignans by Oxidative Coupling Reaction. II. Oxidative Coupling Reaction of Methyl (E)-3-(4,5-Dihydroxy-2-methoxyphenyl)propenoate and Lipid Peroxidation Inhibitory Effects of the Produced Lignans
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