Studies on Uricosuric Diuretics. III. Substituted 1,3-Dioxolo[4,5-f]-1,2-benzisoxazole-6-carboxylic Acids and 1,3-Dioxolo[4,5-g]-1,2-benzisoxazole-7-carboxylic Acids
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概要
- 論文の詳細を見る
A series of substituted 1,3-dioxolo[4,5-f]-1,2-benzisoxazole-6-carboxylic acids 13 and 1,3-dioxolo[4,5-g]-1,2-benzisozazole-7-carboxylic acids 14 were synthesized and evaluated for diuretic and uricosuric activities in rats. Most of the benzisoxazole derivatives 13 and 14 showed potent diuretic activities. Moderate uricosuric activities were also found in 14a, 14b, and 14f.
- 社団法人日本薬学会の論文
- 1992-01-25
著者
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田中 晴子
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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佐藤 晴彦
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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古賀 弘
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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段 孝
Exploratory Research Laboratories, Chugai Pharmaceutical Co., Ltd.,
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小沼 悦郎
Exploratory Research Laboratories, Chugai Pharmaceutical Co., Ltd.,
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青木 文弥
Exploratory Research Laboratories, Chugai Pharmaceutical Co., Ltd.,
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青木 文弥
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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小沼 悦郎
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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Onuma Etsuro
Fuji Gotemba Research Laboratories Chugai Pharmaceutical Co. Ltd.
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Onuma Etsuro
Kamakura Research Laboratories Chugai Pharmaceutical Co. Ltd.
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段 孝
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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