Studies on Uricosuric Diuretics. I. : Syntheses and Activities of Xanthonyloxyacetic Acids and Dihydrofuroxanthone-2-carboxylic Acids
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概要
- 論文の詳細を見る
A series of substituted xanthonyloxyacetic acids (5 and 6), 1,2-dihydrofuro[2,3-c]xanthone-2-carboxylic acids (7) and 2,3-dihydrofuro[3,2-b]xanthone-2-carboxylic acids (8) were synthesized and tested for diuretic and uricosuric activities in rats. Most of the xanthon-3-yloxyacetic acids (5) and 7 showed potent diuretic activities, while 8 had lower activities. Uricosuric activities were found in 5c, 5f, 5k, 5m, 5o, 5p, 5r, 7m, 7p and 8q.
- 社団法人日本薬学会の論文
- 1990-05-25
著者
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田中 晴子
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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佐藤 晴彦
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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古賀 弘
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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段 孝
Exploratory Research Laboratories, Chugai Pharmaceutical Co., Ltd.,
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小沼 悦郎
Exploratory Research Laboratories, Chugai Pharmaceutical Co., Ltd.,
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小沼 悦郎
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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Onuma Etsuro
Fuji Gotemba Research Laboratories Chugai Pharmaceutical Co. Ltd.
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Onuma Etsuro
Kamakura Research Laboratories Chugai Pharmaceutical Co. Ltd.
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段 孝
Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.
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- Studies on Uricosuric Diuretics. I. : Syntheses and Activities of Xanthonyloxyacetic Acids and Dihydrofuroxanthone-2-carboxylic Acids
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